Table 1 The 11 differentially expressed Ferroptosis drivers-related genes in TGF-β2-treated or -untreated pLECs
Gene name | Gene description | Log2FoldChange | Change | P-value | Adj. P-value |
|---|---|---|---|---|---|
SMAD7 | SMAD family member 7 | 1.992841 | Up | 1.49E-112 | 3.84E-110 |
DPP4 | Dipeptidyl peptidase 4 | -2.462277 | Down | 1.27E-107 | 2.87E-105 |
LGMN | Legumain | 1.337992 | Up | 2.63E-97 | 5.26E-95 |
NOX4 | NADPH oxidase 4 | 2.363958 | Up | 5.57E-63 | 5.63E-61 |
NDRG1 | N-myc downstream regulated 1 | 1.27335 | Up | 3.79E-40 | 2.27E-38 |
SLC7A11 | Solute carrier family 7 member 1 | -1.345309 | Down | 1.43E-18 | 3.48E-17 |
IL1B | Interleukin 1 beta | -4.420076 | Down | 8.24E-10 | 1.02E-08 |
KLF2 | Kruppel like factor 2 | 1.355188 | Up | 4.35E-08 | 4.48E-07 |
CHAC1 | ChaC glutathione specific gammaglutamylcyclotransferase 1 | 1.332998 | Up | 2.59E-07 | 2.42E-06 |
AQP5 | Aquaporin 5 | -6.051828 | Down | 1.72E-05 | 1.24E-04 |
CYGB | Cytoglobin | -1.539514 | Down | 1.95E-05 | 1.39E-04 |