Table 2 The 18 differentially expressed Ferroptosis suppressors-related genes in TGF-β2-treated or -untreated pLECs
Gene name | Gene description | Log2FoldChange | Change | P-value | Adj. P-value |
|---|---|---|---|---|---|
NQO1 | NAD(P)H quinone dehydrogenase 1 | -1.225004 | Down | 7.59E-152 | 3.90E-149 |
CAV1 | Caveolin 1 | -1.671334 | Down | 4.42E-119 | 1.26E-116 |
NT5DC2 | 5’-nucleotidase domain containing 2 | 1.52302 | Up | 1.64E-110 | 3.99E-108 |
BEX1 | Brain expressed X-linked 1 | -2.701982 | Down | 6.52E-110 | 1.54E-107 |
CP | Ceruloplasmin | -2.3792 | Down | 2.07E-73 | 2.59E-71 |
NEDD4L | Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -1.547678 | Down | 2.87E-48 | 2.01E-46 |
MGST1 | Microsomal glutathione S-transferase 1 | -1.502248 | Down | 1.63E-39 | 9.54E-38 |
AKR1C3 | Aldo–keto reductase family 1 member C3 | -1.883406 | Down | 3.61E-35 | 1.82E-33 |
ALDH3A2 | Aldehyde dehydrogenase 3 family member A2 | -1.111655 | Down | 3.69E-35 | 1.86E-33 |
SOX2 | SRY-box 2 | -1.614247 | Down | 1.42E-29 | 5.77E-28 |
PARP14 | Poly(ADP-ribose) polymerase family member 14 | -1.069349 | Down | 1.22E-26 | 4.32E-25 |
SLC7A11 | Solute carrier family 7 member 11 | -1.345309 | Down | 1.43E-18 | 3.48E-17 |
KIF20A | Kinesin family member 20A | -1.181047 | Down | 3.10E-08 | 3.25E-07 |
LCN2 | Lipocalin 2 | -1.231111 | Down | 7.60E-08 | 7.57E-07 |
ETV4 | ETS variant 4 | 1.891098 | Up | 5.31E-06 | 4.15E-05 |
GDF15 | Growth differentiation factor 15 | -1.17786 | Down | 1.29E-04 | 7.91E-04 |
PDK4 | Pyruvate dehydrogenase kinase 4 | -1.713539 | Down | 7.07E-04 | 3.67E-03 |
AKR1C1 | Aldo–keto reductase family 1 member C1 | -1.357027 | Down | 2.53E-03 | 1.14E-02 |