Table 4 The 11 differentially expressed Ferroptosis unclassified genes in TGF-β2-treated or -untreated pLECs
Gene name | Gene description | Log2FoldChange | Change | P-value | Adj. P-value |
|---|---|---|---|---|---|
TXNRD1 | Thioredoxin reductase 1 | -1.137716 | Down | 4.41E-119 | 1.26E-116 |
CXCL2 | CXC motif chemokine ligand 2 | -2.324465 | Down | 2.62E-60 | 2.50E-58 |
DRD4 | Dopamine receptor D4 | 2.787184 | Up | 2.21E-56 | 1.88E-54 |
VEGFA | Vascular endothelial growth factor A | 1.480892 | Up | 4.20E-53 | 3.37E-51 |
TXNIP | Thioredoxin interacting protein | -1.015813 | Down | 8.56E-34 | 4.12E-32 |
SLC7A11 | Solute carrier family 7 member 11 | -1.345309 | Down | 1.43E-18 | 3.48E-17 |
HIC1 | HIC ZBTB transcriptional repressor 1 | 1.569275 | Up | 7.26E-16 | 1.47E-14 |
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 | -1.293284 | Down | 1.37E-07 | 1.31E-06 |
RGS4 | Regulator of G protein signaling 4 | 2.318594 | Up | 3.19E-06 | 2.57E-05 |
GDF15 | Growth differentiation factor 15 | -1.17786 | Down | 1.29E-04 | 7.91E-04 |
SLC2A12 | Solute carrier family 2 member 12 | -1.078542 | Down | 4.44E-03 | 1.87E-02 |