Table 1 Compares genetic variations in the Omicron BA.2.76 sequence between Jining City and Wuhan-Hu-1
From: Comprehensive genomic analysis of the SARS-CoV-2 Omicron variant BA.2.76 in Jining City, China, 2022
Gene | Protein | Gene mutation site | Protein variation site |
|---|---|---|---|
5’UTR | - | C241T(87/87) | - |
ORF1ab | NSP1 | T670G(87/87), G777A(1/87), C884T(6/87), C1108T(87/87), C1973T(1/87), C2197T(1/87), C2790T(87/87), A2869G(1/87), C3037T(87/87), G4184A(87/87), T4240C(1/87), C4321T(87/87), C7279T(3/87), T7302C(2/87), C7528T(87/87), C7735T(1/87), A9055G(87/87), C9344T(87/87), A9424G(87/87), C9534T(87/87), C9866T(87/87), C10029T(87/87), C10198T(87/87), A10323G(35/87), G10447A(87/87), A10449A(87/87), C10965T(1/87), G11083T(1/87), C11173T(87/87), TCTGGTTTT11288-11296 missing, C12880T(87/87), C14408T(87/87), C14697T(2/87), G14829T(37/87), T15232G(1/87), C15714T(87/87), C15738T(1/87), G16187A(3/87), G16188T(3/87), C16293T(3/87), C17024T(87/87), C17410T(87/87), G18157T(1/87), A18163G(87/87), G19009T(87/87), G19684T(87/87), C19955T(87/87), A20055G(87/87), C20132T(3/87) | S135R(87/87), R171H(1/87) |
NSP2 | R27C(6/87) | ||
PLpro | T24I(87/87), G489S(87/87), I1528T(2/87) | ||
NSP4 | L264F(87/87), T327I(87/87), L438F(87/87), T492I(87/87) | ||
3CLpro | K90R(35/87), P132H(87/87), T304I(1/87) | ||
NSP6 | L37F(1/87), SGF106-108 missing | ||
RdRp | P323L(87/87), M463I(37/87), W598G(1/87), W916Y(3/87) | ||
helicase | S263F(87/87), R392C(87/87) | ||
NSP14 | V40F(1/87), I42V(87/87), D324Y(87/87) | ||
NSP15 | V22L(87/87), T112I(87/87), A171V(3/87) | ||
S | S | C21618T(87/87), TACCCCCTG2633-21641missing, G21987A(87/87), C22120T(3/87), T22200G(87/87), T22304A(87/87), A22491G(2/87), G22578A(87/87), G22599C(87/87), C22674T(87/87), T22679C(87/87), C22686T(87/87), A22688G(87/87), G22775A(87/87), A22786C(87/87), G22813T(87/87), T22882G(87/87), G22992A(87/87), C22995A(87/87), A23013C(87/87), A23040G(87/87), A23055G(87/87), A23063T(87/87), T23075C(87/87), A23173G(1/87), C23202T(1/87), A23403G(87/87), C23525T(87/87), T23599T(87/87), C23604A(87/87), C23854A(87/87), G23948T(87/87), A24424T(87/87), T24469A(87/87), C25000T(87/87) | T19I(87/87), L24S(87/87), PPA25-27 missing(87/87), G142D(87/87), V213G(87/87), Y248N(87/87), K310R(2/87), G339D(87/87), R346T(87/87), S371F(87/87), S373P(87/87), S375F(87/87), T376A(87/87), D405N(87/87), R408S(87/87), K417N(87/87), N440K(87/87), S477N(87/87), T478K(87/87), E484A(87/87), Q493R(87/87), Q498R(87/87), N501Y(87/87), Y505H(87/87), T547I(1/87), D614G(87/87), H655Y(87/87), N679K(87/87), P681H(87/87), N764K(87/87), D796Y(87/87), Q954H(87/87), N969K(87/87) |
ORF3a | ORF3a | C25416T(87/87), C25584T(87/87), C26060T(87/87) | T223I(87/87) |
E | E | C26270T(87/87), C26408T(1/87) | E9I(87/87), S55F(1/87) |
M | M | C26577G(87/87), G26709A(87/87), C26858T(87/87) | Q19E(87/87), A63T(87/87), |
ORF6 | ORF6 | A27259C(87/87), G27382C(87/87), A37383T(87/87), T27384C(87/87) | D61L |
ORF7a | ORF7a | A27458G(1/87) | E22G(1/87) |
ORF8 TIR | - | C27807T(87/87), | - |
ORF8 | ORF8 | C27972T(87/87) | Q27stop (87/87) |
N TIR | - | A28271T(87/87), | - |
N | N | C28311T(87/87), GAGAACGCA28362-28370 deletion, G28881A(87/87), G28882A(87/87), G28883C(87/87), A29510C(87/87) | P13L(87/87), ERS31-33 deletion (87/87), R203K(87/87), G204R(87/87), S413R(87/87), |
3’UTR |  | G29692A(1/87) | - |