Fig. 1

The expression pattern of miR-542-3p during myogenesis. A miR-542-3p was identified as a key candidate miRNA in the skeletal muscle development of goat and porcine, and muscle dysfunction patients. B The sequence alignment analysis of miR-542-3p in different species. The red-marked nucleotides were the seed sequence of miR-542-3p. hsa: homo sapiens; ssc: sus scrofa; chi: capra hircus; mmu: mus musculus; mo: rat; mml: macaca mulatta; eca: equus caballus; ocu: oryctolagus cuniculus. C, D The myoblasts morphology (C) and the expression level of miR-542-3p (D) at day 0, 2, 4, and 6 after myogenic differentiation, scale bar: 100 μm. n = 3, * P < 0.05, ** P < 0.01