Fig. 3
From: Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans
Convergent amino acid substitutions between cetaceans and other marine mammals. (A) The SFTPC protein consists of 192 amino acids. In marine mammals, the 123rd amino acid is mutated from isoleucine (I) to valine (V) and is located in the important functional domain BRICHOS of SFTPC protein. In the phylogenetic tree, blue font represents marine mammals excluding manatees, and black font represents terrestrial mammals. The red pentagram represents the lineage under positive selection. The silhouette pictures are from the PhyloPic (https://www.phylopic.org/). (B) The three-dimensional structure of SFTPC was built using Swiss-Model, and the red markings indicate convergent amino acid site in marine mammals, which are located in the BRICHOS domain