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Fig. 2 | BMC Genomics

Fig. 2

From: Integrated analysis of single-cell and bulk RNA sequencing data reveals prognostic characteristics of lysosome-dependent cell death-related genes in osteosarcoma

Fig. 2

Identification and function analysis of DEGs. (A) Volcano plot (left) and heatmap (right) of DEGs1 between OS and control cohorts in GSE16088. (B) Volcano plot (left) and heatmap (right) of DEGs2 between metastasis and non-metastasis patients with OS in GSE14359. (C) Venn diagram displays the 21 intersection genes on overlapping DEGs1 from GSE16088, DEGs2 from GSE14359 and LCD-related genes. (D) The PPI network of 21 intersection genes. (E) Functional enrichment results for 21 intersection genes. DEGs, differentially expressed genes; OS, osteosarcoma; LCD, lysosomal-dependent cell death, PPI, protein-protein interaction

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BMC Genomics

ISSN: 1471-2164

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