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Table 4 Top 10 GO enrichment and Top 5 KEGG enrichment of characteristic differentially expressed mRNA in 72h reperfusion (spec_72h mRNAs)

From: Integrated bioinformatics analysis of retinal ischemia/reperfusion injury in rats with potential key genes

ID

Description

Counts

P Value

qvalue

Category

GO:0042391

regulation of membrane potential

36

1.10E-08

3.62E-05

GO_BP

GO:0007409

axonogenesis

30

8.09E-06

0.00231256

GO_BP

GO:0034329

cell junction assembly

29

4.63E-06

0.00167271

GO_BP

GO:0031099

regeneration

28

1.88E-08

3.62E-05

GO_BP

GO:0006816

calcium ion transport

27

5.63E-05

0.005831814

GO_BP

GO:0006875

cellular metal ion homeostasis

25

0.000117623

0.008538448

GO_BP

GO:0070588

calcium ion transmembrane transport

24

1.48E-05

0.003109349

GO_BP

GO:0007611

learning or memory

23

2.05E-05

0.003380869

GO_BP

GO:0021537

telencephalon development

23

4.92E-05

0.005433553

GO_BP

GO:0072507

divalent inorganic cation homeostasis

23

8.34E-05

0.006976169

GO_BP

GO:0097060

synaptic membrane

44

3.56E-14

3.56E-14

GO_CC

GO:0099240

intrinsic component of synaptic membrane

34

9.58E-16

9.58E-16

GO_CC

GO:0031012

extracellular matrix

34

1.05E-09

1.05E-09

GO_CC

GO:0030312

external encapsulating structure

34

1.19E-09

1.19E-09

GO_CC

GO:0099699

integral component of synaptic membrane

33

5.27E-16

5.27E-16

GO_CC

GO:0045211

postsynaptic membrane

33

6.12E-12

6.12E-12

GO_CC

GO:0043235

receptor complex

32

1.61E-08

1.61E-08

GO_CC

GO:1902495

transmembrane transporter complex

30

2.10E-08

2.10E-08

GO_CC

GO:1990351

transporter complex

30

8.39E-08

8.39E-08

GO_CC

GO:0099572

postsynaptic specialization

30

2.25E-06

2.25E-06

GO_CC

GO:0005216

ion channel activity

37

6.51E-11

1.83E-08

GO_MF

GO:0015267

channel activity

37

1.27E-09

7.95E-08

GO_MF

GO:0022803

passive transmembrane transporter activity

37

1.27E-09

7.95E-08

GO_MF

GO:0022836

gated channel activity

33

1.54E-11

8.65E-09

GO_MF

GO:0005261

cation channel activity

31

4.54E-10

4.20E-08

GO_MF

GO:0046873

metal ion transmembrane transporter activity

27

8.98E-06

0.000229803

GO_MF

GO:0005543

phospholipid binding

24

0.0007170

0.010205534

GO_MF

GO:0015276

ligand-gated ion channel activity

20

1.60E-10

3.01E-08

GO_MF

GO:0022834

ligand-gated channel activity

20

2.40E-10

3.29E-08

GO_MF

GO:0005244

voltage-gated ion channel activity

20

1.10E-07

3.65E-06

GO_MF

rno04080

Neuroactive ligand-receptor interaction

32

6.58E-10

1.51E-07

KEGG

rno04723

Retrograde endocannabinoid signaling

17

9.88E-08

4.54E-06

KEGG

rno04024

cAMP signaling pathway

17

1.87E-05

0.00039076

KEGG

rno04020

Calcium signaling pathway

17

9.93E-05

0.00189851

KEGG

rno04726

Serotonergic synapse

16

3.06E-08

2.34E-06

KEGG