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Table 1 Sequences and coordinates of the guides that were used for CRISPR edition

From: A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study

Guide

RNA sequence (5’-3’)

GRCm38/mm10 coordinates

G1 (Gjb6)

ACGGCAGAAGGUGCGCAUUGAGG

chr14:57,124,415–57,124,437

G2 (Gjb6)

CUGCCCGAAAGUUUAUACGUGGG

chr14:57,124,476–57,124,498

G3 (Cryl1)

CGCCAUGGCAGAUCCGGGCCUGG

chr14:57,398,443–57,398,465

G4 (Cryl1)

GCGGGUCGCGCGCCAGAAUAAGG

chr14:57,398,505–57,398,527

  1. In bold, PAM sequences
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BMC Genomics

ISSN: 1471-2164

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