Table 4 Description of key DEGs of M. intracellulare under acidic and oxidative stress conditions

OCU_47950

narU

Nitrogen metabolism

8.25

-1.04

OCU_48030

narK3

8.70

1.03

OCU_12100

narG

8.85

1.01

OCU_12110

narH

7.53

1.07

OCU_12130

narI

6.77

1.09

OCU_48070

nirB

30.68

-1.10

OCU_48080

nirD

30.66

-1.13

OCU_01750

gltB

2.17

-1.05

OCU_01760

gltD

2.01

-1.04

OCU_07280

narL

-2.87

-1.22

OCU_12120

narJ

7.46

1.12

OCU_10620

kdpA

Potassium limitation

3.12

1.12

OCU_10610

kdpB

5.28

1.24

OCU_10600

kdpC

3.91

1.00

OCU_09670

mprB

Membrane stress

2.41

1.05

OCU_09660

mprA

3.17

1.03

OCU_09690

pepD

2.55

-1.04

OCU_10630

trcS

Heat shock, membrane stress

-10.11

1.14

OCU_10640

trcR

-4.10

1.06

OCU_36170

glnD

Glutamate metabolism

2.12

-1.00

OCU_36180

glnB

2.16

-1.08

OCU_15790

cysN

Sulfur metabolism

2.14

-1.06

OCU_15800

cysD

2.30

-1.03

OCU_18650

cysH

2.27

-1.05

OCU_18660

ferredoxin 2

2.45

-1.03

OCU_21500

ferredoxin

13.48

5.64

OCU_20490

formate dehydrogenase

111.19

1.01

OCU_21100

cysQ

2.32

-1.05

OCU_00740

dnaB

DNA replication

-1.07

2.62

OCU_03510

dinG

-1.60

2.48

OCU_22700

Conserved hypothetical protein

1.17

4.32

OCU_04360

Possible DNA polymerase

1.42

3.09

OCU_41260

nei2 (endonuclease)

DNA repair

2.26

2.38

OCU_12600

DNA-3-methyladenine glycosylase I

1.56

2.21

OCU_29740

uvrB

3.03

2.71

OCU_39940

uvrD2

1.54

2.22

OCU_39980

Probable ATP-dependent DNA helicase

4.06

5.36

OCU_34590

recA

1.24

2.28

OCU_33030

ruvC

-1.38

2.25

OCU_42300

groEL1

Heat shock response

3.47

3.07

OCU_45770

groEL2

Lipoarabinomannan biosynthesis

4.78

3.73