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Volume 11 Supplement 4

Ninth International Conference on Bioinformatics (InCoB2010): Computational Biology

Proceedings

Edited by Christian Schönbach, Kenta Nakai, Tin Wee Tan and Shoba Ranganathan

Asia Pacific Bioinformatics Network (APBioNet) Ninth International Conference on Bioinformatics (InCoB2010). Go to conference site.

Tokyo, Japan26-28 September 2010

  1. The 2010 annual conference of the Asia Pacific Bioinformatics Network (APBioNet), Asia’s oldest bioinformatics organisation formed in 1998, was organized as the 9th International Conference on Bioinformatics (InC...

    Authors: Shoba Ranganathan, Christian Schönbach, Kenta Nakai and Tin Wee Tan

    Citation: BMC Genomics 2010 11(Suppl 4):S1

    Content type: Introduction

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  2. Nucleosome, the fundamental unit of chromatin, is formed by wrapping nearly 147bp of DNA around an octamer of histone proteins. This histone core has many variants that are different from each other by their b...

    Authors: Ngoc Tu Le, Tu Bao Ho and Bich Hai Ho

    Citation: BMC Genomics 2010 11(Suppl 4):S3

    Content type: Proceedings

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  3. When characterizing the structural topology of proteins, protein secondary structure (PSS) plays an important role in analyzing and modeling protein structures because it represents the local conformation of a...

    Authors: Hsin-Nan Lin, Ting-Yi Sung, Shinn-Ying Ho and Wen-Lian Hsu

    Citation: BMC Genomics 2010 11(Suppl 4):S4

    Content type: Proceedings

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  4. MicroRNAs (miRNAs) are small noncoding RNAs about 22 nt long that negatively regulate gene expression at the post-transcriptional level. Their key effects on various biological processes, e.g., embryonic devel...

    Authors: Zhen Yang, Fei Ren, Changning Liu, Shunmin He, Gang Sun, Qian Gao, Lei Yao, Yangde Zhang, Ruoyu Miao, Ying Cao, Yi Zhao, Yang Zhong and Haitao Zhao

    Citation: BMC Genomics 2010 11(Suppl 4):S5

    Content type: Proceedings

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  5. Nucleic acid hybridization is an extensively adopted principle in biomedical research, in which the performance of any hybridization-based method depends on the specificity of probes to their targets. To deter...

    Authors: Shu-Hwa Chen, Chen-Zen Lo, Sheng-Yao Su, Bao-Han Kuo, Chao A Hsiung and Chung-Yen Lin

    Citation: BMC Genomics 2010 11(Suppl 4):S6

    Content type: Proceedings

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  6. While the accuracy and precision of deep sequencing data is significantly better than those obtained by the earlier generation of hybridization-based high throughput technologies, the digital nature of deep se...

    Authors: Manhong Dai, Robert C Thompson, Christopher Maher, Rafael Contreras-Galindo, Mark H Kaplan, David M Markovitz, Gil Omenn and Fan Meng

    Citation: BMC Genomics 2010 11(Suppl 4):S7

    Content type: Proceedings

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  7. MicroRNAs (miRNAs) are endogenous non-protein-coding RNA genes which exist in a wide variety of organisms, including animals, plants, virus and even unicellular organisms. Medaka (Oryzias latipes) is a useful mod...

    Authors: Sung-Chou Li, Wen-Ching Chan, Meng-Ru Ho, Kuo-Wang Tsai, Ling-Yueh Hu, Chun-Hung Lai, Chun-Nan Hsu, Pung-Pung Hwang and Wen-chang Lin

    Citation: BMC Genomics 2010 11(Suppl 4):S8

    Content type: Proceedings

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  8. With the increase in genomic and transcriptomic data produced by the recent advancements in next generation sequencers and microarrays, it is now easier than ever to conduct large-scale comparative genomic stu...

    Authors: Atsushi Ogura, Masa-aki Yoshida, Mutsumi Fukuzaki and Jun Sese

    Citation: BMC Genomics 2010 11(Suppl 4):S9

    Content type: Proceedings

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  9. Orthologues are genes in different species that are related through divergent evolution from a common ancestor and are expected to have similar functions. Many databases have been created to describe orthologo...

    Authors: Yizhen Jia, Thomas KF Wong, You-Qiang Song, Siu-Ming Yiu and David K Smith

    Citation: BMC Genomics 2010 11(Suppl 4):S11

    Content type: Proceedings

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  10. RNA editing is a transcript-based layer of gene regulation. To date, no systemic study on RNA editing of plant nuclear genes has been reported. Here, a transcriptome-wide search for editing sites in nuclear tr...

    Authors: Yijun Meng, Dijun Chen, YongFeng Jin, Chuanzao Mao, Ping Wu and Ming Chen

    Citation: BMC Genomics 2010 11(Suppl 4):S12

    Content type: Proceedings

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  11. In eukaryotes, the cell is divided into several compartments enclosed by unitary membranes. Such compartmentalization is critical for cells to restrict different pathways to be carried out in different subcell...

    Authors: Min Zhao and Hong Qu

    Citation: BMC Genomics 2010 11(Suppl 4):S13

    Content type: Proceedings

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  12. The UPP (ubiquitin proteasome pathway) is the major proteolytic system in the cytosol and nucleus of all eukaryotic cells which regulates cellular events, including mitotis, differentiation, signal transductio...

    Authors: Abhinav Grover, Ashutosh Shandilya, Virendra S Bisaria and Durai Sundar

    Citation: BMC Genomics 2010 11(Suppl 4):S15

    Content type: Proceedings

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  13. Appropriate regulation of respective gene expressions is a bottleneck for the realization of artificial biological systems inside living cells. The modification of several promoter sequences is required to ach...

    Authors: Shotaro Ayukawa, Akio Kobayashi, Yusaku Nakashima, Hidemasa Takagi, Shogo Hamada, Masahiko Uchiyama, Katsuyuki Yugi, Satoshi Murata, Yasubumi Sakakibara, Masami Hagiya, Masayuki Yamamura and Daisuke Kiga

    Citation: BMC Genomics 2010 11(Suppl 4):S16

    Content type: Proceedings

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  14. Variety of information relating between genome and the pathological findings in disease will yield a wealth of clues to discover new function, the role of genes and pathways, and future medicine. In addition t...

    Authors: Kazuro Shimokawa, Kaoru Mogushi, Satoshi Shoji, Atsuko Hiraishi, Keisuke Ido, Hiroshi Mizushima and Hiroshi Tanaka

    Citation: BMC Genomics 2010 11(Suppl 4):S19

    Content type: Proceedings

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  15. The identification of B-cell epitopes on antigens has been a subject of intense research as the knowledge of these markers has great implications for the development of peptide-based diagnostics, therapeutics ...

    Authors: Lawrence JK Wee, Diane Simarmata, Yiu-Wing Kam, Lisa FP Ng and Joo Chuan Tong

    Citation: BMC Genomics 2010 11(Suppl 4):S21

    Content type: Proceedings

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  16. Changes to the glycosylation profile on HIV gp120 can influence viral pathogenesis and alter AIDS disease progression. The characterization of glycosylation differences at the sequence level is inadequate as t...

    Authors: Paul D Yoo, Yung Shwen Ho, Jason Ng, Michael Charleston, Nitin K Saksena, Pengyi Yang and Albert Y Zomaya

    Citation: BMC Genomics 2010 11(Suppl 4):S22

    Content type: Proceedings

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  17. Human disease genes can be distinguished from essential (embryonically lethal) and non-disease genes using gene attributes. Such attributes include gene age, tissue specificity of expression, regulatory capaci...

    Authors: Shivashankar H Nagaraj, Aaron Ingham and Antonio Reverter

    Citation: BMC Genomics 2010 11(Suppl 4):S23

    Content type: Proceedings

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  18. Mutation impact extraction is a hitherto unaccomplished task in state of the art mutation extraction systems. Protein mutations and their impacts on protein properties are hidden in scientific literature, maki...

    Authors: Jonas B Laurila, Nona Naderi, René Witte, Alexandre Riazanov, Alexandre Kouznetsov and Christopher JO Baker

    Citation: BMC Genomics 2010 11(Suppl 4):S24

    Content type: Proceedings

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  19. Nuclear Factor kappa B (NF-κB) is a transcription factor involved in the regulation of cell signaling responses and is a key regulator of cellular processes involved in the immune response, differentiation, ce...

    Authors: Abhinav Grover, Ashutosh Shandilya, Ankita Punetha, Virendra S Bisaria and Durai Sundar

    Citation: BMC Genomics 2010 11(Suppl 4):S25

    Content type: Proceedings

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  20. The increasing numbers of 3D compounds and protein complexes stored in databases contribute greatly to current advances in biotechnology, being employed in several pharmaceutical and industrial applications. H...

    Authors: Daniel L Clinciu, Yen-Fu Chen, Cheng-Neng Ko, Chi-Chun Lo and Jinn-Moon Yang

    Citation: BMC Genomics 2010 11(Suppl 4):S26

    Content type: Proceedings

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  21. The 2010 International Conference on Bioinformatics, InCoB2010, which is the annual conference of the Asia-Pacific Bioinformatics Network (APBioNet) has agreed to publish conference papers in compliance with t...

    Authors: Tin Wee Tan, Joo Chuan Tong, Asif M Khan, Mark de Silva, Kuan Siong Lim and Shoba Ranganathan

    Citation: BMC Genomics 2010 11(Suppl 4):S27

    Content type: Perspective

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