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Volume 11 Supplement 4

Ninth International Conference on Bioinformatics (InCoB2010): Computational Biology

Proceedings

Edited by Christian Schönbach, Kenta Nakai, Tin Wee Tan and Shoba Ranganathan

Asia Pacific Bioinformatics Network (APBioNet) Ninth International Conference on Bioinformatics (InCoB2010). Go to conference site.

Tokyo, Japan26-28 September 2010

  1. The 2010 annual conference of the Asia Pacific Bioinformatics Network (APBioNet), Asia’s oldest bioinformatics organisation formed in 1998, was organized as the 9th International Conference on Bioinformatics (InC...

    Authors: Shoba Ranganathan, Christian Schönbach, Kenta Nakai and Tin Wee Tan
    Citation: BMC Genomics 2010 11(Suppl 4):S1
  2. Nucleosome, the fundamental unit of chromatin, is formed by wrapping nearly 147bp of DNA around an octamer of histone proteins. This histone core has many variants that are different from each other by their b...

    Authors: Ngoc Tu Le, Tu Bao Ho and Bich Hai Ho
    Citation: BMC Genomics 2010 11(Suppl 4):S3
  3. When characterizing the structural topology of proteins, protein secondary structure (PSS) plays an important role in analyzing and modeling protein structures because it represents the local conformation of a...

    Authors: Hsin-Nan Lin, Ting-Yi Sung, Shinn-Ying Ho and Wen-Lian Hsu
    Citation: BMC Genomics 2010 11(Suppl 4):S4
  4. MicroRNAs (miRNAs) are small noncoding RNAs about 22 nt long that negatively regulate gene expression at the post-transcriptional level. Their key effects on various biological processes, e.g., embryonic devel...

    Authors: Zhen Yang, Fei Ren, Changning Liu, Shunmin He, Gang Sun, Qian Gao, Lei Yao, Yangde Zhang, Ruoyu Miao, Ying Cao, Yi Zhao, Yang Zhong and Haitao Zhao
    Citation: BMC Genomics 2010 11(Suppl 4):S5
  5. Nucleic acid hybridization is an extensively adopted principle in biomedical research, in which the performance of any hybridization-based method depends on the specificity of probes to their targets. To deter...

    Authors: Shu-Hwa Chen, Chen-Zen Lo, Sheng-Yao Su, Bao-Han Kuo, Chao A Hsiung and Chung-Yen Lin
    Citation: BMC Genomics 2010 11(Suppl 4):S6
  6. While the accuracy and precision of deep sequencing data is significantly better than those obtained by the earlier generation of hybridization-based high throughput technologies, the digital nature of deep se...

    Authors: Manhong Dai, Robert C Thompson, Christopher Maher, Rafael Contreras-Galindo, Mark H Kaplan, David M Markovitz, Gil Omenn and Fan Meng
    Citation: BMC Genomics 2010 11(Suppl 4):S7
  7. MicroRNAs (miRNAs) are endogenous non-protein-coding RNA genes which exist in a wide variety of organisms, including animals, plants, virus and even unicellular organisms. Medaka (Oryzias latipes) is a useful mod...

    Authors: Sung-Chou Li, Wen-Ching Chan, Meng-Ru Ho, Kuo-Wang Tsai, Ling-Yueh Hu, Chun-Hung Lai, Chun-Nan Hsu, Pung-Pung Hwang and Wen-chang Lin
    Citation: BMC Genomics 2010 11(Suppl 4):S8
  8. With the increase in genomic and transcriptomic data produced by the recent advancements in next generation sequencers and microarrays, it is now easier than ever to conduct large-scale comparative genomic stu...

    Authors: Atsushi Ogura, Masa-aki Yoshida, Mutsumi Fukuzaki and Jun Sese
    Citation: BMC Genomics 2010 11(Suppl 4):S9
  9. Orthologues are genes in different species that are related through divergent evolution from a common ancestor and are expected to have similar functions. Many databases have been created to describe orthologo...

    Authors: Yizhen Jia, Thomas KF Wong, You-Qiang Song, Siu-Ming Yiu and David K Smith
    Citation: BMC Genomics 2010 11(Suppl 4):S11
  10. RNA editing is a transcript-based layer of gene regulation. To date, no systemic study on RNA editing of plant nuclear genes has been reported. Here, a transcriptome-wide search for editing sites in nuclear tr...

    Authors: Yijun Meng, Dijun Chen, YongFeng Jin, Chuanzao Mao, Ping Wu and Ming Chen
    Citation: BMC Genomics 2010 11(Suppl 4):S12
  11. In eukaryotes, the cell is divided into several compartments enclosed by unitary membranes. Such compartmentalization is critical for cells to restrict different pathways to be carried out in different subcell...

    Authors: Min Zhao and Hong Qu
    Citation: BMC Genomics 2010 11(Suppl 4):S13
  12. The UPP (ubiquitin proteasome pathway) is the major proteolytic system in the cytosol and nucleus of all eukaryotic cells which regulates cellular events, including mitotis, differentiation, signal transductio...

    Authors: Abhinav Grover, Ashutosh Shandilya, Virendra S Bisaria and Durai Sundar
    Citation: BMC Genomics 2010 11(Suppl 4):S15
  13. Appropriate regulation of respective gene expressions is a bottleneck for the realization of artificial biological systems inside living cells. The modification of several promoter sequences is required to ach...

    Authors: Shotaro Ayukawa, Akio Kobayashi, Yusaku Nakashima, Hidemasa Takagi, Shogo Hamada, Masahiko Uchiyama, Katsuyuki Yugi, Satoshi Murata, Yasubumi Sakakibara, Masami Hagiya, Masayuki Yamamura and Daisuke Kiga
    Citation: BMC Genomics 2010 11(Suppl 4):S16
  14. Variety of information relating between genome and the pathological findings in disease will yield a wealth of clues to discover new function, the role of genes and pathways, and future medicine. In addition t...

    Authors: Kazuro Shimokawa, Kaoru Mogushi, Satoshi Shoji, Atsuko Hiraishi, Keisuke Ido, Hiroshi Mizushima and Hiroshi Tanaka
    Citation: BMC Genomics 2010 11(Suppl 4):S19
  15. The identification of B-cell epitopes on antigens has been a subject of intense research as the knowledge of these markers has great implications for the development of peptide-based diagnostics, therapeutics ...

    Authors: Lawrence JK Wee, Diane Simarmata, Yiu-Wing Kam, Lisa FP Ng and Joo Chuan Tong
    Citation: BMC Genomics 2010 11(Suppl 4):S21
  16. Changes to the glycosylation profile on HIV gp120 can influence viral pathogenesis and alter AIDS disease progression. The characterization of glycosylation differences at the sequence level is inadequate as t...

    Authors: Paul D Yoo, Yung Shwen Ho, Jason Ng, Michael Charleston, Nitin K Saksena, Pengyi Yang and Albert Y Zomaya
    Citation: BMC Genomics 2010 11(Suppl 4):S22
  17. Human disease genes can be distinguished from essential (embryonically lethal) and non-disease genes using gene attributes. Such attributes include gene age, tissue specificity of expression, regulatory capaci...

    Authors: Shivashankar H Nagaraj, Aaron Ingham and Antonio Reverter
    Citation: BMC Genomics 2010 11(Suppl 4):S23
  18. Mutation impact extraction is a hitherto unaccomplished task in state of the art mutation extraction systems. Protein mutations and their impacts on protein properties are hidden in scientific literature, maki...

    Authors: Jonas B Laurila, Nona Naderi, René Witte, Alexandre Riazanov, Alexandre Kouznetsov and Christopher JO Baker
    Citation: BMC Genomics 2010 11(Suppl 4):S24
  19. Nuclear Factor kappa B (NF-κB) is a transcription factor involved in the regulation of cell signaling responses and is a key regulator of cellular processes involved in the immune response, differentiation, ce...

    Authors: Abhinav Grover, Ashutosh Shandilya, Ankita Punetha, Virendra S Bisaria and Durai Sundar
    Citation: BMC Genomics 2010 11(Suppl 4):S25
  20. The increasing numbers of 3D compounds and protein complexes stored in databases contribute greatly to current advances in biotechnology, being employed in several pharmaceutical and industrial applications. H...

    Authors: Daniel L Clinciu, Yen-Fu Chen, Cheng-Neng Ko, Chi-Chun Lo and Jinn-Moon Yang
    Citation: BMC Genomics 2010 11(Suppl 4):S26
  21. The 2010 International Conference on Bioinformatics, InCoB2010, which is the annual conference of the Asia-Pacific Bioinformatics Network (APBioNet) has agreed to publish conference papers in compliance with t...

    Authors: Tin Wee Tan, Joo Chuan Tong, Asif M Khan, Mark de Silva, Kuan Siong Lim and Shoba Ranganathan
    Citation: BMC Genomics 2010 11(Suppl 4):S27

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