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Volume 11 Supplement 5

Proceedings of the 5th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2009)

Proceedings

http://www.ab3c.org

5th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2009). Go to conference site.

Angra Dos Reis, RJ, Brazil18-22 October 2009

  1. The link between reproductive life history and incidence of ovarian tumors is well known. Periods of reduced ovulations may confer protection against ovarian cancer. Using phenotypic data available for mouse, ...

    Authors: Ulises Urzúa, Garrison A Owens, Gen-Mu Zhang, James M Cherry, John J Sharp and David J Munroe
    Citation: BMC Genomics 2010 11(Suppl 5):S1
  2. The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial ...

    Authors: Leandra Linhares-Lacerda, Marcelo Ribeiro-Alves, Ana Cristina Martins de Almeida Nogueira, Daniella Areas Mendes-da-Cruz, Danielle Aparecida Magalhães, Mireille Dardenne, Geraldo Aleixo Passos and Wilson Savino
    Citation: BMC Genomics 2010 11(Suppl 5):S2
  3. Retrieving pertinent information from biological scientific literature requires cutting-edge text mining methods which may be able to recognize the meaning of the very ambiguous names of biological entities. A...

    Authors: Roney S Coimbra, Dana E Vanderwall and Guilherme C Oliveira
    Citation: BMC Genomics 2010 11(Suppl 5):S3
  4. Alternative splicing (AS) is a central mechanism in the generation of genomic complexity and is a major contributor to transcriptome and proteome diversity. Alterations of the splicing process can lead to dere...

    Authors: Elisa N Ferreira, Maria CR Rangel, Pedro F Galante, Jorge E de Souza, Gustavo C Molina, Sandro J de Souza and Dirce M Carraro
    Citation: BMC Genomics 2010 11(Suppl 5):S4
  5. Cathepsin B (catB) is a promising target for anti-cancer drug design due to its implication in several steps of tumorigenesis. catB activity and inhibition are pH-dependent, making it difficult to identify eff...

    Authors: Mauricio GS Costa, Paulo R Batista, Cláudio S Shida, Charles H Robert, Paulo M Bisch and Pedro G Pascutti
    Citation: BMC Genomics 2010 11(Suppl 5):S5
  6. Molecular docking simulation is the Rational Drug Design (RDD) step that investigates the affinity between protein receptors and ligands. Typically, molecular docking algorithms consider receptors as rigid bod...

    Authors: Karina S Machado, Ana T Winck, Duncan DA Ruiz and Osmar Norberto de Souza
    Citation: BMC Genomics 2010 11(Suppl 5):S6
  7. G. diazotrophicus and A. vinelandii are aerobic nitrogen-fixing bacteria. Although oxygen is essential for the survival of these organisms, it irreversibly inhibits nitrogenase, the complex responsible for nitrog...

    Authors: Letícia MS Lery, Mainá Bitar, Mauricio GS Costa, Shaila CS Rössle and Paulo M Bisch
    Citation: BMC Genomics 2010 11(Suppl 5):S7
  8. The need to manage large amounts of data is a clear demand for laboratories nowadays. The use of Laboratory Information Management Systems (LIMS) to achieve this is growing each day. A LIMS is a complex comput...

    Authors: Alexandre Melo, Alessandra Faria-Campos, Daiane Mariele DeLaat, Rodrigo Keller, Vinícius Abreu and Sérgio Campos
    Citation: BMC Genomics 2010 11(Suppl 5):S8
  9. The genome-wide identification of both morbid genes, i.e., those genes whose mutations cause hereditary human diseases, and druggable genes, i.e., genes coding for proteins whose modulation by small molecules ...

    Authors: Pedro R Costa, Marcio L Acencio and Ney Lemke
    Citation: BMC Genomics 2010 11(Suppl 5):S9
  10. A large number of probabilistic models used in sequence analysis assign non-zero probability values to most input sequences. To decide when a given probability is sufficient the most common way is bayesian bin...

    Authors: Ariane Machado-Lima, André Yoshiaki Kashiwabara and Alan Mitchell Durham
    Citation: BMC Genomics 2010 11(Suppl 5):S10

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