Volume 12 Supplement 2
Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2010
Proceedings
Edited by Xiaohua Tony Hu and Taesung Park
IEEE International Conference on Bioinformatics and Biomedicine 2010. Go to
conference site.
Hong Kong, P. R. China18-21 December 2010
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Content type: Proceedings
Strains of Mycobacterium tuberculosis complex (MTBC) can be classified into major lineages based on their genotype. Further subdivision of major lineages into sublineages requires multiple biomarkers along with m...
Authors: Cagri Ozcaglar, Amina Shabbeer, Scott Vandenberg, Bülent Yener and Kristin P Bennett
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Content type: Proceedings
Proximity-based methods and co-evolution-based phylogenetic profiles methods have been successfully used for the identification of functionally related genes. Proximity-based methods are effective for physical...
Authors: Vikas Rao Pejaver and Sun Kim
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Content type: Proceedings
Reassortments are events in the evolution of the genome of influenza (flu), whereby segments of the genome are exchanged between different strains. As reassortments have been implicated in major human pandemic...
Authors: Alisa Yurovsky and Bernard M E Moret
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Content type: Proceedings
A major goal of metagenomics is to characterize the microbial composition of an environment. The most popular approach relies on 16S rRNA sequencing, however this approach can generate biased estimates due to ...
Authors: Bo Liu, Theodore Gibbons, Mohammad Ghodsi, Todd Treangen and Mihai Pop
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Content type: Proceedings
Analysing gene expression data from microarray technologies is a very important task in biology and medicine, and particularly in cancer diagnosis. Different from most other popular methods in high dimensional...
Authors: Zhenyu Wang and Vasile Palade
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Content type: Proceedings
There is a large amount of inconsistency in gene structure annotations of bacterial strains. This inconsistency is a frustrating impedance to effective comparative genomic analysis of bacterial strains in prom...
Authors: Michal Wozniak, Limsoon Wong and Jerzy Tiuryn
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Content type: Proceedings
Genomic read alignment involves mapping (exactly or approximately) short reads from a particular individual onto a pre-sequenced reference genome of the same species. Because all individuals of the same specie...
Authors: M Oğuzhan Külekci, Wing-Kai Hon, Rahul Shah, Jeffrey Scott Vitter and Bojian Xu
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Content type: Proceedings
Metagenomic assembly is a challenging problem due to the presence of genetic material from multiple organisms. The problem becomes even more difficult when short reads produced by next generation sequencing te...
Authors: Anveshi Charuvaka and Huzefa Rangwala
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Content type: Proceedings
Detecting epistatic interactions plays a significant role in improving pathogenesis, prevention, diagnosis and treatment of complex human diseases. A recent study in automatic detection of epistatic interactio...
Authors: Bing Han and Xue-wen Chen
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Content type: Proceedings
CpG islands are important regions in DNA. They usually appear at the 5’ end of genes containing GC-rich dinucleotides. When DNA methylation occurs, gene regulation is affected and it sometimes leads to carcino...
Authors: Leah Spontaneo and Nick Cercone
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Content type: Proceedings
Newly microarray technologies yield large-scale datasets. The microarray datasets are usually presented in 2D matrices, where rows represent genes and columns represent experimental conditions. Systematic anal...
Authors: Junwan Liu, Zhoujun Li, Xiaohua Hu, Yiming Chen and EK Park
