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BMC Genomics

Volume 13 Supplement 6

Selected articles from the IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) 2011

Research

Edited by Ranadip Pal, Yufei Huang and Yidong Chen

This supplement has not been supported by sponsorship or other external funding.

IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) 2011. Go to conference site.

San Antonio, TX, USA4-6 December 2011

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  1. Content type: Research

    Mass spectrometry is a complex technique used for large-scale protein profiling with clinical and pharmaceutical applications. While individual components in the system have been studied extensively, little wo...

    Authors: Youting Sun, Ulisses Braga-Neto and Edward R Dougherty

    Citation: BMC Genomics 2012 13(Suppl 6):S2

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  2. Content type: Research

    Oxidative stress is a consequence of normal and abnormal cellular metabolism and is linked to the development of human diseases. The effective functioning of the pathway responding to oxidative stress protects...

    Authors: Sriram Sridharan, Ritwik Layek, Aniruddha Datta and Jijayanagaram Venkatraj

    Citation: BMC Genomics 2012 13(Suppl 6):S4

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  3. Content type: Research

    Estrogens control multiple functions of hormone-responsive breast cancer cells. They regulate diverse physiological processes in various tissues through genomic and non-genomic mechanisms that result in activa...

    Authors: Heng-Yi Wu, Pengyue Zheng, Guanglong Jiang, Yunlong Liu, Kenneth P Nephew, Tim HM Huang and Lang Li

    Citation: BMC Genomics 2012 13(Suppl 6):S6

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  4. Content type: Research

    A current challenge in gene annotation is to define the gene function in the context of the network of relationships instead of using single genes. The inference of gene networks (GNs) has emerged as an approa...

    Authors: Fábio FR Vicente, Fabrício M Lopes, Ronaldo F Hashimoto and Roberto M Cesar Jr

    Citation: BMC Genomics 2012 13(Suppl 6):S7

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  5. Content type: Research

    The Steady State (SS) probability distribution is an important quantity needed to characterize the steady state behavior of many stochastic biochemical networks. In this paper, we propose an efficient and accu...

    Authors: Shahriar Karim, Gregery T Buzzard and David M Umulis

    Citation: BMC Genomics 2012 13(Suppl 6):S10

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  6. Content type: Research

    Molecularly targeted agents (MTAs) are increasingly used for cancer treatment, the goal being to improve the efficacy and selectivity of cancer treatment by developing agents that block the growth of cancer ce...

    Authors: Xiangfang Li, Lijun Qian, Jianping Hua, Michael L Bittner and Edward R Dougherty

    Citation: BMC Genomics 2012 13(Suppl 6):S11

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  7. Content type: Research

    Despite initial response in adjuvant chemotherapy, ovarian cancer patients treated with the combination of paclitaxel and carboplatin frequently suffer from recurrence after few cycles of treatment, and the un...

    Authors: Fang-Han Hsu, Erchin Serpedin, Tzu-Hung Hsiao, Alexander JR Bishop, Edward R Dougherty and Yidong Chen

    Citation: BMC Genomics 2012 13(Suppl 6):S13

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  8. Content type: Research

    Advances in whole genome profiling have revolutionized the cancer research field, but at the same time have raised new bioinformatics challenges. For next generation sequencing (NGS), these include data storag...

    Authors: Benjamin AT Rodriguez, David Frankhouser, Mark Murphy, Michael Trimarchi, Hok-Hei Tam, John Curfman, Rita Huang, Michael WY Chan, Hung-Cheng Lai, Deval Parikh, Bryan Ball, Sebastian Schwind, William Blum, Guido Marcucci, Pearlly Yan and Ralf Bundschuh

    Citation: BMC Genomics 2012 13(Suppl 6):S14

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  9. Content type: Research

    Genome-wide association studies (GWAS) have generated a wealth of valuable genotyping data for complex diseases/traits. A large proportion of these data are embedded with many weakly associated markers that ha...

    Authors: Peilin Jia and Zhongming Zhao

    Citation: BMC Genomics 2012 13(Suppl 6):S15

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  10. Content type: Research

    Whole genome sequencing enables a high resolution view of the human genome and provides unique insights into genome structure at an unprecedented scale. There have been a number of tools to infer copy number v...

    Authors: Angel Janevski, Vinay Varadan, Sitharthan Kamalakaran, Nilanjana Banerjee and Nevenka Dimitrova

    Citation: BMC Genomics 2012 13(Suppl 6):S16

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  11. Content type: Research

    Network pharmacology has emerged as a new topic of study in recent years. It aims to study the myriad relationships among proteins, drugs, and disease phenotypes. The concept of molecular connectivity maps has...

    Authors: Hui Huang, Xiaogang Wu, Ragini Pandey, Jiao Li, Guoling Zhao, Sara Ibrahim and Jake Y Chen

    Citation: BMC Genomics 2012 13(Suppl 6):S17

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  12. Content type: Research

    One method to understand and evaluate an experiment that produces a large set of genes, such as a gene expression microarray analysis, is to identify overrepresentation or enrichment for biological pathways. B...

    Authors: Mark S Doderer, Zachry Anguiano, Uthra Suresh, Ravi Dashnamoorthy, Alexander JR Bishop and Yidong Chen

    Citation: BMC Genomics 2012 13(Suppl 6):S18

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  13. Content type: Research

    Until recently, sequencing has primarily been carried out in large genome centers which have invested heavily in developing the computational infrastructure that enables genomic sequence analysis. The recent a...

    Authors: Uday S Evani, Danny Challis, Jin Yu, Andrew R Jackson, Sameer Paithankar, Matthew N Bainbridge, Adinarayana Jakkamsetti, Peter Pham, Cristian Coarfa, Aleksandar Milosavljevic and Fuli Yu

    Citation: BMC Genomics 2012 13(Suppl 6):S19

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