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  1. Plant fungal pathogens can rapidly evolve and adapt to new environmental conditions in response to sudden changes of host populations in agro-ecosystems. However, the genomic basis of their host adaptation, es...

    Authors: Chongjing Xia, Meinan Wang, Chuntao Yin, Omar E. Cornejo, Scot H. Hulbert and Xianming Chen
    Citation: BMC Genomics 2018 19:664
    Content type: Research article Published on:

  2. So far, biocontrol agent selection has been performed mainly by time consuming in vitro confrontation tests followed by extensive trials in greenhouse and field. An alternative approach is offered by applicati...

    Authors: Francesca Fanelli, Vania Cosma Liuzzi, Antonio Francesco Logrieco and Claudio Altomare
    Citation: BMC Genomics 2018 19:662
    Content type: Research article Published on:

  3. Pectin is a major component and structural polysaccharide of the primary cell walls and middle lamella of higher plants. Pectate lyase (PEL, EC 4.2.2.2), a cell wall modification enzyme, degrades de-esterified...

    Authors: Huiru Sun, Pengbo Hao, Qiang Ma, Meng Zhang, Yuan Qin, Hengling Wei, Junji Su, Hantao Wang, Lijiao Gu, Nuohan Wang, Guoyuan Liu and Shuxun Yu
    Citation: BMC Genomics 2018 19:661
    Content type: Research article Published on:

  4. To explore long non-coding RNA (lncRNA), mRNA and circular RNA (circRNA) expression profiles and their biological functions in the pathogenesis of kidney stones in ethylene glycol-induced urolithiasis rats.

    Authors: Yanan Cao, Xiaowei Gao, Yue Yang, Zhi Ye, E. Wang and Zhitao Dong
    Citation: BMC Genomics 2018 19:660
    Content type: Research article Published on:

  5. Intermittent fasting and time-restricted diets are associated with lower risk biomarkers for cardio-metabolic disease. The shared mechanisms underpinning the similar physiological response to these events is n...

    Authors: Alexessander Couto Alves, Craig A. Glastonbury, Julia S. El-Sayed Moustafa and Kerrin S. Small
    Citation: BMC Genomics 2018 19:659
    Content type: Research article Published on:

  7. Improving resistance to mastitis, one of the costliest diseases in dairy production, has become an important objective in dairy cattle breeding. However, mastitis resistance is influenced by many genes involve...

    Authors: Zexi Cai, Bernt Guldbrandtsen, Mogens Sandø Lund and Goutam Sahana
    Citation: BMC Genomics 2018 19:656
    Content type: Research article Published on:

  8. The transient middle cerebral artery occlusion (tMCAO) model is used for studying the molecular mechanisms of ischemic damage and neuroprotection. Numerous studies have demonstrated the role of individual gene...

    Authors: Lyudmila V. Dergunova, Ivan B. Filippenkov, Vasily V. Stavchansky, Alina E. Denisova, Vadim V. Yuzhakov, Sergey A. Mozerov, Leonid V. Gubsky and Svetlana A. Limborska
    Citation: BMC Genomics 2018 19:655
    Content type: Research article Published on:

  9. Members of the genus Naegleria are free-living eukaryotes with the capability to transform from the amoeboid form into resting cysts or moving flagellates in response to environmental conditions. More than 40 spe...

    Authors: Nicole Liechti, Nadia Schürch, Rémy Bruggmann and Matthias Wittwer
    Citation: BMC Genomics 2018 19:654
    Content type: Research article Published on:

  10. The challenges when developing a good de novo transcriptome assembler include how to deal with read errors and sequence repeats. Almost all de novo assemblers utilize a de Bruijn graph, with which complexity g...

    Authors: Seokhyun Yoon, Daeseung Kim, Keunsoo Kang and Woong June Park
    Citation: BMC Genomics 2018 19:653
    Content type: Software Published on:

  11. Enterococcus faecium though commensal in the human gut, few strains provide a beneficial effect to humans as probiotics while few are responsible for the nosocomial infection. Comparative genomics of E. faecium c...

    Authors: Vikas C. Ghattargi, Meghana A. Gaikwad, Bharati S. Meti, Yogesh S. Nimonkar, Kunal Dixit, Om Prakash, Yogesh S. Shouche, Shrikant P. Pawar and Dhiraj P. Dhotre
    Citation: BMC Genomics 2018 19:652
    Content type: Research article Published on:

  12. Short read DNA sequencing technologies have revolutionized genome assembly by providing high accuracy and throughput data at low cost. But it remains challenging to assemble short read data, particularly for l...

    Authors: Alina Ott, James C. Schnable, Cheng-Ting Yeh, Linjiang Wu, Chao Liu, Heng-Cheng Hu, Clifton L. Dalgard, Soumik Sarkar and Patrick S. Schnable
    Citation: BMC Genomics 2018 19:651
    Content type: Research article Published on:

  14. Hydractinia symbiolongicarpus, a colonial cnidarian, is a tractable model system for many cnidarian-specific and general biological questions. Until recently, tests of gene function in Hydractinia have relied on ...

    Authors: Steven M. Sanders, Zhiwei Ma, Julia M. Hughes, Brooke M. Riscoe, Gregory A. Gibson, Alan M. Watson, Hakima Flici, Uri Frank, Christine E. Schnitzler, Andreas D. Baxevanis and Matthew L. Nicotra
    Citation: BMC Genomics 2018 19:649
    Content type: Research article Published on:

  15. Tartary buckwheat (Fagopyrum tataricum Gaertn.) is a widely cultivated medicinal and edible crop with excellent economic and nutritional value. The development of tartary buckwheat seeds is a very complex process...

    Authors: Moyang Liu, Zhaotang Ma, Tianrun Zheng, Wenjun Sun, Yanjun Zhang, Weiqiong Jin, Junyi Zhan, Yuntao Cai, Yujia Tang, Qi Wu, Zizhong Tang, Tongliang Bu, Chenglei Li and Hui Chen
    Citation: BMC Genomics 2018 19:648
    Content type: Research article Published on:

  16. Enterohemorrhagic Escherichia coli (EHEC) O26:H11/H−, the most common non-O157 serotype causing hemolytic uremic syndrome worldwide, are evolutionarily highly dynamic with new pathogenic clones emerging rapidly. ...

    Authors: Lucia Karnisova, Monika Marejkova, Hana Hrbackova, Alexander Mellmann, Helge Karch, Angelika Fruth, Pavel Drevinek, Kveta Blahova, Martina Bielaszewska and Jaroslav Nunvar
    Citation: BMC Genomics 2018 19:647
    Content type: Research article Published on:

  18. Rhizobia are alpha-proteobacteria commonly found in soil and root nodules of legumes. It was recently reported that nitrogen-fixing rhizobia also inhabit legume seeds. In this study, we examined whole-genome s...

    Authors: Alejandro Aguilar, Yolanda Mora, Araceli Dávalos, Lourdes Girard, Jaime Mora and Humberto Peralta
    Citation: BMC Genomics 2018 19:645
    Content type: Research article Published on:

  19. Chronic lung infections caused by Pseudomonas aeruginosa are a significant cause of morbidity and mortality in people with cystic fibrosis (CF). Shared P. aeruginosa strains, that can be transmitted between patie...

    Authors: Bryan A. Wee, Anna S. Tai, Laura J. Sherrard, Nouri L. Ben Zakour, Kirt R. Hanks, Timothy J. Kidd, Kay A. Ramsay, Iain Lamont, David M. Whiley, Scott C. Bell and Scott A. Beatson
    Citation: BMC Genomics 2018 19:644
    Content type: Research article Published on:

  20. Exposure to heat stress suppresses poultry immune responses, which can increase susceptibility to infectious diseases and, thereby, intensify the negative effects of heat on poultry welfare and performance. Id...

    Authors: Melissa S. Monson, Angelica G. Van Goor, Christopher M. Ashwell, Michael E. Persia, Max F. Rothschild, Carl J. Schmidt and Susan J. Lamont
    Citation: BMC Genomics 2018 19:643
    Content type: Research article Published on:

  21. Fusarium head blight (FHB) of wheat in North America is caused mostly by the fungal pathogen Fusarium graminearum (Fg). Upon exposure to Fg, wheat initiates a series of cellular responses involving massive transc...

    Authors: Youlian Pan, Ziying Liu, Hélène Rocheleau, François Fauteux, Yunli Wang, Curt McCartney and Thérèse Ouellet
    Citation: BMC Genomics 2018 19:642
    Content type: Research article Published on:

  22. Soybean is not only an important oil crop, but also an important source of edible protein and industrial raw material. Yield-traits and quality-traits are increasingly attracting the attention of breeders. The...

    Authors: Yanwei Zhang, Wei Li, Yanhui Lin, Lifeng Zhang, Caijie Wang and Ran Xu
    Citation: BMC Genomics 2018 19:641
    Content type: Research article Published on:

  23. In the current scenario, the drug-resistant tuberculosis is a significant challenge in the control of tuberculosis worldwide. In order to investigate the in vivo evolution of drug-resistant M. tuberculosis, the p...

    Authors: Yuhui Xu, Fei Liu, Suting Chen, Jiannan Wu, Yongfei Hu, Baoli Zhu and Zhaogang Sun
    Citation: BMC Genomics 2018 19:640
    Content type: Research article Published on:

  24. MicroRNAs (miRNAs) are small non-coding RNAs that bind messenger RNAs and promote their degradation or repress their translation. There is increasing evidence of miRNAs playing an important role in alcohol rel...

    Authors: Pratyaydipta Rudra, Wen J. Shi, Pamela Russell, Brian Vestal, Boris Tabakoff, Paula Hoffman, Katerina Kechris and Laura Saba
    Citation: BMC Genomics 2018 19:639
    Content type: Research article Published on:

  25. Hair follicles (HFs), upon development, undergo repetitive cycles of growth (anagen), regression (catagen), and rest (telogen). The transition between the stages is determined by multiple molecular signals, in...

    Authors: Chao Li, Yan Li, Guangxian Zhou, Ye Gao, Sen Ma, Yulin Chen, Jiuzhou Song and Xiaolong Wang
    Citation: BMC Genomics 2018 19:638
    Content type: Research article Published on:

  26. Although most genes in mammalian genomes have multiple isoforms, an ongoing debate is whether these isoforms are all functional as well as the extent to which they increase the functional repertoire of the gen...

    Authors: Shamsuddin A. Bhuiyan, Sophia Ly, Minh Phan, Brandon Huntington, Ellie Hogan, Chao Chun Liu, James Liu and Paul Pavlidis
    Citation: BMC Genomics 2018 19:637
    Content type: Research article Published on:

  27. Canine brucellosis, due to Brucella canis, is a worldwide zoonosis that remains endemic in South America, including Brazil. Implementation of powerful whole-genome sequencing approaches allowed exploring the Bruc...

    Authors: Acácia Ferreira Vicente, Guillaume Girault, Yannick Corde, Mateus Souza Ribeiro Mioni, Lara Borges Keid, Maryne Jay, Jane Megid and Virginie Mick
    Citation: BMC Genomics 2018 19:636
    Content type: Research article Published on:

  28. Delivery of colostrum within the first several hours after birth is vital for establishing successful passive immunity in neonatal dairy calves. However, it is unclear whether a difference in colostrum feeding...

    Authors: Zhixiong He, Amanda Fischer, Yang Song, Michael Steele and Le Luo Guan
    Citation: BMC Genomics 2018 19:635
    Content type: Research article Published on:

  29. Mitochondria are organelles that fulfill a fundamental role in cell bioenergetics, as well as in other processes like cell signaling and death. Small non-coding RNAs (sncRNA) are now being considered as pivota...

    Authors: Eduardo Larriba, Eduardo Rial and Jesús del Mazo
    Citation: BMC Genomics 2018 19:634
    Content type: Research article Published on:

  31. Fusarium circinatum is a pressing threat to the cultivation of many economically important pine tree species. Efforts to develop effective disease management strategies can be aided by investigating the molecular...

    Authors: Erik A. Visser, Jill L. Wegrzyn, Alexander A. Myburg and Sanushka Naidoo
    Citation: BMC Genomics 2018 19:632
    Content type: Research article Published on:

  32. Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modificati...

    Authors: Fengrui Wu, Yong Liu, Qingqing Wu, Dengkun Li, Ling Zhang, Xiaoqing Wu, Rong Wang, Di Zhang, Shaorong Gao and Wenyong Li
    Citation: BMC Genomics 2018 19:631
    Content type: Database Published on:

  33. During hair growth, cortical cells emerging from the proliferative follicle bulb rapidly undergo a differentiation program and synthesize large amounts of hair keratin proteins. In this process, HOXC13 is one ...

    Authors: Shanhe Wang, Zhixin Luo, Yuelang Zhang, Dan Yuan, Wei Ge and Xin Wang
    Citation: BMC Genomics 2018 19:630
    Content type: Research article Published on:

  34. Long-term exposure to elevated levels of free fatty acids (FFAs) is deleterious for beta-cell function and may contribute to development of type 2 diabetes mellitus (T2DM). Whereas mechanisms of impaired gluco...

    Authors: Ernest Sargsyan, Jing Cen, Kirsten Roomp, Reinhard Schneider and Peter Bergsten
    Citation: BMC Genomics 2018 19:629
    Content type: Research article Published on:

  35. Bees are confronting several environmental challenges, including the intermingled effects of malnutrition and disease. Intuitively, pollen is the healthiest nutritional choice, however, commercial substitutes,...

    Authors: Farida Azzouz-Olden, Arthur Hunt and Gloria DeGrandi-Hoffman
    Citation: BMC Genomics 2018 19:628
    Content type: Research article Published on:

  36. The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation anti-gonococcal pharmaceuticals. The development and succ...

    Authors: Ian P. Francis, Epshita A. Islam, Adam C. Gower, Yazdani B. Shaik-Dasthagirisaheb, Scott D. Gray-Owen and Lee M. Wetzler
    Citation: BMC Genomics 2018 19:627
    Content type: Research article Published on:

  37. Both growth and nutritional traits are important economic traits of Crassostrea gigas (C. gigas) in industry. But few work has been done to study the genetic architecture of nutritional traits of the oyster. In t...

    Authors: Chunyan Li, Jinpeng Wang, Kai Song, Jie Meng, Fei Xu, Li Li and Guofan Zhang
    Citation: BMC Genomics 2018 19:626
    Content type: Research article Published on:

  38. Pontimonas salivibrio strain CL-TW6T (=KCCM 90105 = JCM18206) was characterized as the type strain of a new genus within the Actinobacterial family Microbacteriaceae. It was isolated from a coastal marine environ...

    Authors: Byung Cheol Cho, Stephen C. Hardies, Gwang Il Jang and Chung Yeon Hwang
    Citation: BMC Genomics 2018 19:625
    Content type: Research article Published on:

  39. The new genomic technologies have provided novel insights into the genetics of interactions between vectors, viruses and hosts, which are leading to advances in the control of arboviruses of medical importance...

    Authors: Ramiro Morales-Hojas, Malcolm Hinsley, Irina M. Armean, Rhiannon Silk, Lara E. Harrup, Asier Gonzalez-Uriarte, Eva Veronesi, Lahcen Campbell, Dana Nayduch, Christopher Saski, Walter J. Tabachnick, Paul Kersey, Simon Carpenter and Mark Fife
    Citation: BMC Genomics 2018 19:624
    Content type: Research article Published on:

  40. Genomic regions repressed for DNA replication, resulting in either delayed replication in S phase or underreplication in polyploid cells, are thought to be controlled by inhibition of replication origin activa...

    Authors: Brian L. Hua, George W. Bell, Helena Kashevsky, Jessica R. Von Stetina and Terry L. Orr-Weaver
    Citation: BMC Genomics 2018 19:623
    Content type: Research article Published on:

  41. The success of early reproductive events depends on an appropriate communication between gametes/embryos and the oviduct. Extracellular vesicles (EVs) contained in oviductal secretions have been suggested as n...

    Authors: C. Almiñana, G. Tsikis, V. Labas, R. Uzbekov, J. C. da Silveira, S. Bauersachs and P. Mermillod
    Citation: BMC Genomics 2018 19:622
    Content type: Research article Published on:

  42. Coagulase negative staphylococci (CoNS) are commensal bacteria on human skin. Staphylococcus lugdunensis is a unique CoNS which produces various virulence factors and may, like S. aureus, cause severe infections,...

    Authors: Xavier Argemi, Dorota Matelska, Krzysztof Ginalski, Philippe Riegel, Yves Hansmann, Jochen Bloom, Martine Pestel-Caron, Sandrine Dahyot, Jérémie Lebeurre and Gilles Prévost
    Citation: BMC Genomics 2018 19:621
    Content type: Research article Published on:

  44. In livestock, residual variance has been studied because of the interest to improve uniformity of production. Several studies have provided evidence that residual variance is partially under genetic control; h...

    Authors: Laiza Helena de Souza Iung, Herman Arend Mulder, Haroldo Henrique de Rezende Neves and Roberto Carvalheiro
    Citation: BMC Genomics 2018 19:619
    Content type: Research article Published on:

  45. The marine polychaete annelid Platynereis dumerilii has recently emerged as a prominent organism for the study of development, evolution, stem cells, regeneration, marine ecology, chronobiology and neurobiology w...

    Authors: Hsien-Chao Chou, Natalia Acevedo-Luna, Julie A. Kuhlman and Stephan Q. Schneider
    Citation: BMC Genomics 2018 19:618
    Content type: Database Published on:

  46. In the past decade, many new paramyxoviruses that do not belong to any of the seven established genera in the family Paramyxoviridae have been discovered. Amongst them are J-virus (JPV), Beilong virus (BeiPV) and...

    Authors: Bert Vanmechelen, Magda Bletsa, Lies Laenen, Ana Rita Lopes, Valentijn Vergote, Leen Beller, Ward Deboutte, Miša Korva, Tatjana Avšič Županc, Joëlle Goüy de Bellocq, Sophie Gryseels, Herwig Leirs, Philippe Lemey, Bram Vrancken and Piet Maes
    Citation: BMC Genomics 2018 19:617
    Content type: Research article Published on:

  47. The leaves of tea plants (Camellia sinensis) are used to produce tea, which is one of the most popular beverages consumed worldwide. The nutritional value and health benefits of tea are mainly related to three ab...

    Authors: Yuling Tai, Chun Liu, Shuwei Yu, Hua Yang, Jiameng Sun, Chunxiao Guo, Bei Huang, Zhaoye Liu, Yi Yuan, Enhua Xia, Chaoling Wei and Xiaochun Wan
    Citation: BMC Genomics 2018 19:616
    Content type: Research article Published on:

  48. Apis mellifera scutellata and A.m. capensis (the Cape honey bee) are western honey bee subspecies indigenous to the Republic of South Africa (RSA). Both bees are important for biological and economic reasons. Fir...

    Authors: Amin Eimanifar, Samantha A. Brooks, Tomas Bustamante and James D. Ellis
    Citation: BMC Genomics 2018 19:615
    Content type: Research article Published on:

  49. Mixed, polyclonal Mycobacterium tuberculosis infection occurs in natural populations. Developing an effective method for detecting such cases is important in measuring the success of treatment and reconstruction ...

    Authors: Benjamin Sobkowiak, Judith R. Glynn, Rein M. G. J. Houben, Kim Mallard, Jody E. Phelan, José Afonso Guerra-Assunção, Louis Banda, Themba Mzembe, Miguel Viveiros, Ruth McNerney, Julian Parkhill, Amelia C. Crampin and Taane G. Clark
    Citation: BMC Genomics 2018 19:613
    Content type: Research article Published on:

  50. The molecular mechanisms underlying bacterial cell death due to stresses or bactericidal antibiotics are complex and remain puzzling. Due to the current crisis of antibiotic resistance, development of effectiv...

    Authors: Sardar Karash and Young Min Kwon
    Citation: BMC Genomics 2018 19:610
    Content type: Research article Published on:

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BMC Genomics

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