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  1. Comprehensive analysis of multi-omics data is crucial for accurately formulating effective treatment plans for complex diseases. Supervised ensemble methods have gained popularity in recent years for multi-omi...

    Authors: Jiahui Wang, Nanqing Liao, Xiaofei Du, Qingfeng Chen and Bizhong Wei
    Citation: BMC Genomics 2024 25:86
  2. Genomic heterozygosity has been shown to confer a health advantage in humans and play a protective role in complex diseases. Given osteoarthritis (OA) is a highly polygenic disease, we set out to determine if ...

    Authors: Robert Gill, Ming Liu, Guang Sun, Andrew Furey, Tim Spector, Proton Rahman and Guangju Zhai
    Citation: BMC Genomics 2024 25:85
  3. Venoms have evolved independently over a hundred times in the animal kingdom to deter predators and/or subdue prey. Venoms are cocktails of various secreted toxins, whose origin and diversification provide an ...

    Authors: Axel Touchard, Valentine Barassé, Jean-Michel Malgouyre, Michel Treilhou, Christophe Klopp and Elsa Bonnafé
    Citation: BMC Genomics 2024 25:84
  4. Protein phosphatases type 2C (PP2C) are heavily involved in plant growth and development, hormone-related signaling pathways and the response of various biotic and abiotic stresses. However, a comprehensive repor...

    Authors: Pan Zhang, Deqi Liu, Jiawei Ma, Chong Sun, Zhaofei Wang, Yongxing Zhu, Xuemei Zhang and Yiqing Liu
    Citation: BMC Genomics 2024 25:83
  5. Glucosidase II beta subunit (GluIIß), encoded from PRKCSH, is a subunit of the glucosidase II enzyme responsible for quality control of N-linked glycoprotein folding and suppression of GluIIß led to inhibitory ef...

    Authors: Worapong Khaodee, Guo Xiyuan, Moe Thi Thi Han, Chatchai Tayapiwatana, Sawitree Chiampanichayakul, Songyot Anuchapreeda and Ratchada Cressey
    Citation: BMC Genomics 2024 25:82
  6. The expression of biological traits is modulated by genetics as well as the environment, and the level of influence exerted by the latter may vary across characteristics. Photosynthetic traits in plants are co...

    Authors: Huiying Gong, Ziyang Zhou, Chenhao Bu, Deqiang Zhang, Qing Fang, Xiao-Yu Zhang and Yuepeng Song
    Citation: BMC Genomics 2024 25:81
  7. Hemocytes are immune cells that patrol the mosquito hemocoel and mediate critical cellular defense responses against pathogens. However, despite their importance, a comprehensive transcriptome of these cells w...

    Authors: Banhisikha Saha, Colton M McNinch, Stephen Lu, Margaret C.W. Ho, Stephanie Serafim De Carvalho and Carolina Barillas-Mury
    Citation: BMC Genomics 2024 25:80
  8. Drought poses a major threat to agricultural production and thus food security. Understanding the processes shaping plant responses to water deficit is essential for global food safety. Though many studies exa...

    Authors: Alina Klaus, Caroline Marcon and Frank Hochholdinger
    Citation: BMC Genomics 2024 25:79
  9. Local adaptation is a key evolutionary process that enhances the growth of plants in their native habitat compared to non-native habitats, resulting in patterns of adaptive genetic variation across the entire ...

    Authors: Joanna Meger, Bartosz Ulaszewski, Daniel J. Chmura and Jarosław Burczyk
    Citation: BMC Genomics 2024 25:78
  10. The Peruvian ‘chanque’ or Chilean ‘loco’ Concholepas concholepas is an economically, ecologically, and culturally important muricid gastropod heavily exploited by artisanal fisheries in the temperate southeastern...

    Authors: J. Antonio Baeza, M. Teresa González, Julia D. Sigwart, Carola Greve and Stacy Pirro
    Citation: BMC Genomics 2024 25:77
  11. We previously reported a modification of the CUT&Tag method (NTU-CAT) that allows genome-wide histone modification analysis in individual preimplantation embryos. In the present study, NTU-CAT was further simp...

    Authors: Yiren Zeng, Yoichiro Hoshino, Kazuki Susami, Shinnosuke Honda, Naojiro Minami and Shuntaro Ikeda
    Citation: BMC Genomics 2024 25:75
  12. Plant growth-regulating factors (GRFs) and GRF-interacting factors (GIFs) interact with each other and collectively have important regulatory roles in plant growth, development, and stress responses. Therefore...

    Authors: Xinghao Chen, Jun Zhang, Shijie Wang, Hongyu Cai, Minsheng Yang and Yan Dong
    Citation: BMC Genomics 2024 25:74
  13. Long noncoding RNAs (lncRNAs) are integral to a plethora of critical cellular biological processes, including the regulation of gene expression, cell differentiation, and the development of tumors and cancers....

    Authors: Guanghui Li, Peihao Bai, Cheng Liang and Jiawei Luo
    Citation: BMC Genomics 2024 25:73
  14. Temperature is an important environment factor that is critical to the survival and growth of crustaceans. However, the mechanisms by which crustaceans detect changes in temperature are still unclear. The tran...

    Authors: Yichen Qian, Qiaoling Yu, Jun Zhang, Yaoyao Han, Xi Xie and Dongfa Zhu
    Citation: BMC Genomics 2024 25:72
  15. Nonspecific orbital inflammation (NSOI) is an idiopathic, persistent, and proliferative inflammatory condition affecting the orbit, characterized by polymorphous lymphoid infiltration. Its pathogenesis and pro...

    Authors: Zixuan Wu, Na Li, Yuan Gao, Liyuan Cao, Xiaolei Yao and Qinghua Peng
    Citation: BMC Genomics 2024 25:71

    The Correction to this article has been published in BMC Genomics 2024 25:224

  16. Dorper and Tan sheep are renowned for their rapid growth and exceptional meat quality, respectively. Previous research has provided evidence of the impact of gut microbiota on breed characteristics. The precis...

    Authors: Yuhao Ma, Ganxian Cai, Jianfei Chen, Xue Yang, Guoying Hua, Deping Han, Xinhai Li, Dengzhen Feng and Xuemei Deng
    Citation: BMC Genomics 2024 25:70
  17. The yak is a symbol of the Qinghai-Tibet Plateau and provides important basic resources for human life on the plateau. Domestic yaks have been subjected to strong artificial selection and environmental pressur...

    Authors: Wei Peng, Changqi Fu, Shi Shu, Guowen Wang, Hui Wang, Binglin Yue, Ming Zhang, Xinrui Liu, Yaxin Liu, Jun Zhang, Jincheng Zhong and Jiabo Wang
    Citation: BMC Genomics 2024 25:69
  18. Costaceae, commonly known as the spiral ginger family, consists of approximately 120 species distributed in the tropical regions of South America, Africa, and Southeast Asia, of which some species have importa...

    Authors: Dong-Mei Li, Yan-Gu Pan, Hai-Lin Liu, Bo Yu, Dan Huang and Gen-Fa Zhu
    Citation: BMC Genomics 2024 25:68
  19. Rye (Secale cereale), one of the drought and cold-tolerant crops, is an important component of the Triticae Dumortier family of Gramineae plants. Basic helix-loop-helix (bHLH), an important family of transcriptio...

    Authors: Xingyu Chen, Caimei Yao, Jiahao Liu, Jintao Liu, Jingmei Fang, Hong Deng, Qian Yao, Tairan Kang and Xiaoqiang Guo
    Citation: BMC Genomics 2024 25:67
  20. The ongoing evolution of the Next Generation Sequencing (NGS) technologies has led to the production of genomic data on a massive scale. While tools for genomic data integration and analysis are becoming incre...

    Authors: Emile Mardoc, Mamadou Dia Sow, Sébastien Déjean and Jérôme Salse
    Citation: BMC Genomics 2024 25:66
  21. Pod shell thickness (PST) is an important agronomic trait of peanut because it affects the ability of shells to resist pest infestations and pathogen attacks, while also influencing the peanut shelling process...

    Authors: Hongfei Liu, Zheng Zheng, Ziqi Sun, Feiyan Qi, Juan Wang, Mengmeng Wang, Wenzhao Dong, Kailu Cui, Mingbo Zhao, Xiao Wang, Meng Zhang, Xiaohui Wu, Yue Wu, Dandan Luo, Bingyan Huang, Zhongxin Zhang…
    Citation: BMC Genomics 2024 25:65
  22. Largemouth bass (Micropterus salmoides) has significant economic value as a high-yielding fish species in China’s freshwater aquaculture industry. Determining the major genes related to growth traits and identify...

    Authors: Jixiang Hua, Chunyi Zhong, Wenhua Chen, Jianjun Fu, Jian Wang, Qingchun Wang, Geyan Zhu, Yan Li, Yifan Tao, Maoyou Zhang, Yalun Dong, Siqi Lu, Wenting Liu and Jun Qiang
    Citation: BMC Genomics 2024 25:64
  23. Vesicular stomatitis virus (VSV) is a typical non-segmented negative-sense RNA virus of the genus Vesiculovirus in the family Rhabdoviridae. VSV can infect a wide range of animals, including humans, with oral bli...

    Authors: Wuweiyi Han, Xiaojuan Fei, Fan Yang, Xintong Sun, Jianshe Yang, Jinxin Qiu, Luhua Zhang, Wenhui Zhang, Guohua Chen, Wei Han, Xiaobo He, Yongsheng Liu and Weike Li
    Citation: BMC Genomics 2024 25:62
  24. Sweetpotato is a typical ‘‘potassium (K+) favoring’’ food crop, which root differentiation process needs a large supply of potassium fertilizer and determine the final root yield. To further understand the regula...

    Authors: Rong Jin, Mengxiao Yan, Guanghua Li, Ming Liu, Peng Zhao, Zhe Zhang, Qiangqiang Zhang, Xiaoya Zhu, Jing Wang, Yongchao Yu, Aijun Zhang, Jun Yang and Zhonghou Tang
    Citation: BMC Genomics 2024 25:61
  25. Beyond the massive amounts of DNA and genes transferred from the protoorganelle genome to the nucleus during the endosymbiotic event that gave rise to the plastids, stretches of plastid DNA of varying size are...

    Authors: Juan Pablo Marczuk-Rojas, Angélica María Álamo-Sierra, Antonio Salmerón, Alfredo Alcayde, Viktor Isanbaev and Lorenzo Carretero-Paulet
    Citation: BMC Genomics 2024 25:60
  26. Central Michigan University (CMU) participated in a state-wide SARS-CoV-2 wastewater monitoring program since 2021. Wastewater samples were collected from on-campus sites and nine off-campus wastewater treatme...

    Authors: Michael J. Conway, Hannah Yang, Lauren A. Revord, Michael P. Novay, Rachel J. Lee, Avery S. Ward, Jackson D. Abel, Maggie R. Williams, Rebecca L. Uzarski and Elizabeth W. Alm
    Citation: BMC Genomics 2024 25:59
  27. Cytochrome P450 monooxygenases (CYP450s) play a crucial role in various biochemical reactions involved in the synthesis of antioxidants, pigments, structural polymers, and defense-related compounds in plants. ...

    Authors: Xiongjian Lin, Binquan Tang, Zhenqin Li, Lei Shi and Hongbo Zhu
    Citation: BMC Genomics 2024 25:58
  28. The disease caused by Riemerella anatipestifer (R. anatipestifer, RA) results in large economic losses to the global duck industry every year. Serovar-related genomic variation, such as the O-antigen and capsular...

    Authors: Zhishuang Yang, Xueqin Yang, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Sai Mao, Qun Gao, Di Sun, Bin Tian…
    Citation: BMC Genomics 2024 25:57
  29. The genomes of species belonging to the genus Colletotrichum harbor a substantial number of cytochrome P450 monooxygenases (CYPs) encoded by a broad diversity of gene families. However, the biological role of the...

    Authors: Jossue Ortiz-Álvarez, Sioly Becerra, Riccardo Baroncelli, César Hernández-Rodríguez, Serenella A. Sukno and Michael R. Thon
    Citation: BMC Genomics 2024 25:56
  30. Feeding costs represent the largest expenditures in beef production. Therefore, the animal efficiency in converting feed in high-quality protein for human consumption plays a major role in the environmental im...

    Authors: Lorena F. Benfica, Luiz F. Brito, Ricardo D. do Bem, Henrique A. Mulim, Joseph Glessner, Larissa G. Braga, Leonardo S. Gloria, Joslaine N. S. G. Cyrillo, Sarah F. M. Bonilha and Maria E. Z. Mercadante
    Citation: BMC Genomics 2024 25:54
  31. Saliva plays a crucial role in shaping the feeding behavior of insects, involving processes such as food digestion and the regulation of interactions between insects and their hosts. Cyrtorhinus lividipennis serv...

    Authors: Fang He, Yang-Wei Gao, Zhuang-Xin Ye, Hai-Jian Huang, Cai-Hong Tian, Chuan-Xi Zhang, Jian-Ping Chen, Jun-Min Li and Jia-Bao Lu
    Citation: BMC Genomics 2024 25:53
  32. Most skin-related traits have been studied in Caucasian genetic backgrounds. A comprehensive study on skin-associated genetic effects on underrepresented populations such as Vietnam is needed to fill the gaps ...

    Authors: Tham Hong Hoang, Duc Minh Vu, Giang Minh Vu, Thien Khac Nguyen, Nguyet Minh Do, Vinh Chi Duong, Thang Luong Pham, Mai Hoang Tran, Ly Thi Khanh Nguyen, Han Thi Tuong Han, Thu-Thuy Can, Thai Hong Pham, Tho Duc Pham, Thanh Hong Nguyen, Huy Phuoc Do, Nam S. Vo…
    Citation: BMC Genomics 2024 25:52
  33. Colorectal cancer (CRC) is one of the world's most common malignancies. Epigenetics is the study of heritable changes in characteristics beyond the DNA sequence. Epigenetic information is essential for maintai...

    Authors: Xia Li, Jingjing Li, Jie Li, Nannan Liu and Liwei Zhuang
    Citation: BMC Genomics 2024 25:51
  34. Even though the Buyei are a recognised ethnic group in southwestern China, there hasn’t been much work done on forensic population genetics, notably using mitochondrial DNA. The sequences and haplogroups of mi...

    Authors: Yuhang Feng, Li Chen, Xiaoxue Wang, Hongling Zhang, Qiyan Wang, Yubo Liu, Xiaoye Jin, Meiqing Yang, Jiang Huang and Zheng Ren
    Citation: BMC Genomics 2024 25:50
  35. The polygenic risk score (PRS) is used to predict the risk of developing common complex diseases or cancers using genetic markers. Although PRS is used in clinical practice to predict breast cancer risk, it is...

    Authors: Joo Young Hong, Jang Hee Han, Seung Hwan Jeong, Cheol Kwak, Hyeon Hoe Kim and Chang Wook Jeong
    Citation: BMC Genomics 2024 25:46
  36. Parameters adversely affecting the contiguity and accuracy of the assemblies from Illumina next-generation sequencing (NGS) are well described. However, past studies generally focused on their additive effects...

    Authors: Zoltán Rádai, Alex Váradi, Péter Takács, Nikoletta Andrea Nagy, Nicholas Schmitt, Eszter Prépost, Gábor Kardos and Levente Laczkó
    Citation: BMC Genomics 2024 25:45
  37. Drug repurposing plays a significant role in providing effective treatments for certain diseases faster and more cost-effectively. Successful repurposing cases are mostly supported by a classical paradigm that...

    Authors: Belén Otero-Carrasco, Esther Ugarte Carro, Lucía Prieto-Santamaría, Marina Diaz Uzquiano, Juan Pedro Caraça-Valente Hernández and Alejandro Rodríguez-González
    Citation: BMC Genomics 2024 25:43
  38. Gene-edited mosquitoes lacking a gamma-interferon-inducible lysosomal thiol reductase-like protein, namely (mosGILTnull) have lower Plasmodium infection, which is linked to impaired ovarian development and immune...

    Authors: Gunjan Arora, Xiaotian Tang, Yingjun Cui, Jing Yang, Yu-Min Chuang, Jayadev Joshi, Andaleeb Sajid, Yuemei Dong, Peter Cresswell, George Dimopoulos and Erol Fikrig
    Citation: BMC Genomics 2024 25:42
  39. Mitochondrial genome abnormalities can lead to mitochondrial dysfunction, which in turn affects cellular biology and is closely associated with the development of various diseases. The demand for mitochondrial...

    Authors: Zehui Feng, Fan Peng, Fanfan Xie, Yang Liu, Huanqin Zhang, Jing Ma, Jinliang Xing and Xu Guo
    Citation: BMC Genomics 2024 25:41
  40. Viral diseases are posing threat to annual production and quality of tobacco in China. Recently, tomato spotted wilt orthotospovirus (TSWV) has been reported to infect three major crops including tobacco. Curr...

    Authors: Ali Kamran, Ying Li, Wanhong Zhang, Yubin Jiao, Tahir Farooq, Yong Wang, Dongyang Liu, Lianqiang Jiang, Lili Shen, Fenglong Wang and Jinguang Yang
    Citation: BMC Genomics 2024 25:40
  41. Scutellaria baicalensis Georgi has been extensively used as a medicinal herb in China for over 2000 years. They may be intentionally or inadvertently substituted or blended with comparable species in the local ma...

    Authors: Zhen Li, Baozhong Duan, Zhongyu Zhou, Hui Fang, Meihua Yang, Conglong Xia, Ying Zhou and Jing Wang
    Citation: BMC Genomics 2024 25:39
  42. Citrus is one of the most valuable fruits worldwide and an economic pillar industry in southern China. Nevertheless, it frequently suffers from undesirable environmental stresses during the growth cycle, which...

    Authors: Ming-Kang Fu, Ying-Na He, Xiao-Yue Yang, Xi Tang, Min Wang and Wen-Shan Dai
    Citation: BMC Genomics 2024 25:37

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