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  1. SerpinB2 is highly expressed in immune and tumor cells and is involved in multiple biological functions, including cell survival and remodeling for disease progression. This study prepared SerpinB2-deficient m...

    Authors: Yin Ji Piao, Hoe Suk Kim, Wonshik Han and Woo Kyung Moon
    Citation: BMC Genomics 2022 23:479
  2. Calling germline SNP variants from bisulfite-converted sequencing data poses a challenge for conventional software, which have no inherent capability to dissociate true polymorphisms from artificial mutations ...

    Authors: Adam Nunn, Christian Otto, Mario Fasold, Peter F Stadler and David Langenberger
    Citation: BMC Genomics 2022 23:477
  3. Genome-scale metabolic network models (GEMs) provide an efficient platform for the comprehensive analysis the physical and biochemical functions of organisms due to their systematic perspective on the study of...

    Authors: Jingjing Li, Yifei Gou, Jiarui Yang, Lingxuan Zhao, Bin Wang, Tong Hao and Jinsheng Sun
    Citation: BMC Genomics 2022 23:475
  4. Tuberous root formation and development is a complex process in sweet potato, which is regulated by multiple genes and environmental factors. However, the regulatory mechanism of tuberous root development is u...

    Authors: Zhaoqin Cai, Zhipeng Cai, Jingli Huang, Aiqin Wang, Aaron Ntambiyukuri, Bimei Chen, Ganghui Zheng, Huifeng Li, Yongmei Huang, Jie Zhan, Dong Xiao and Longfei He
    Citation: BMC Genomics 2022 23:473
  5. Both the protein domains and transcript structures influence protein functional variation. The genomic location of both protein domains and transcript structural features can be described using the genomic coo...

    Authors: Hongwei Wang, Xiaotian Zhang, Shuangcheng Ding, Yujie Huang, Shengyong Wang, Huili Chen, Yuhang Chen and Yuting Li
    Citation: BMC Genomics 2022 23:472
  6. Emerging pathogenic bacteria are an increasing threat to public health. Two recently described species of the genus Aliarcobacter, A. faecis and A. lanthieri, isolated from human or livestock feces, are closely r...

    Authors: Jiacheng Chuan, Anatoly Belov, Michel Cloutier, Xiang Li, Izhar U. H. Khan and Wen Chen
    Citation: BMC Genomics 2022 23:471
  7. The selection of tissue culture–derived somaclonal variants of Giant Cavendish banana (Musa spp., Cavendish sub-group AAA) by the Taiwan Banana Research Institute (TBRI) has resulted in several cultivars resistan...

    Authors: Bo-Han Hou, Yi-Heng Tsai, Ming-Hau Chiang, Shu-Ming Tsao, Shih-Hung Huang, Chih-Ping Chao and Ho-Ming Chen
    Citation: BMC Genomics 2022 23:470
  8. Streptococcus parasuis (S. parasuis) is a close relative of Streptococcus suis (S. suis), composed of former members of S. suis serotypes 20, 22 and 26. S. parasuis could infect pigs and cows, and recently, human...

    Authors: Genglin Guo, Zhuohao Wang, Quan Li, Yanfei Yu, Yubao Li, Zhongming Tan and Wei Zhang
    Citation: BMC Genomics 2022 23:469
  9. T cell acute lymphoblastic leukemia (T-ALL) defines a group of hematological malignancies with heterogeneous aggressiveness and highly variable outcome, making therapeutic decisions a challenging task. We trie...

    Authors: Li-Jun Peng, Yue-Bo Zhou, Mei Geng, Ekaterina Bourova-Flin, Florent Chuffart, Wei-Na Zhang, Tao Wang, Meng-Qing Gao, Meng-Ping Xi, Zhong-Yi Cheng, Jiao-Jiao Zhang, Yuan-Fang Liu, Bing Chen, Saadi Khochbin, Jin Wang, Sophie Rousseaux…
    Citation: BMC Genomics 2022 23:467
  10. Opisthopappus is a major wild source of Asteraceae with resistance to cold and drought. Two species of this genus (Opisthopappus taihangensis and O. longilobus) have been employed as model systems to address the ...

    Authors: Ning Chen, Hao Zhang, En Zang, Zhi-Xia Liu, Ya-Fei Lan, Wei-Li Hao, Shan He, Xing Fan, Gen-Lou Sun and Yi-Ling Wang
    Citation: BMC Genomics 2022 23:466
  11. Type 2 diabetes mellitus (T2DM) has been associated with treatment failure, and the development of drug resistance in tuberculosis (TB). Also, whole-genome sequencing has provided a better understanding and al...

    Authors: Gustavo Adolfo Bermudez-Hernández, Damián Eduardo Pérez-Martínez, Carlos Francisco Madrazo-Moya, Irving Cancino-Muñoz, Iñaki Comas and Roberto Zenteno-Cuevas
    Citation: BMC Genomics 2022 23:465
  12. Ticks represent a major health issue for humans and domesticated animals. Exploring the expression landscape of the tick’s central nervous system (CNS), known as the synganglion, would be an important step in ...

    Authors: Claude Rispe, Caroline Hervet, Nathalie de la Cotte, Romain Daveu, Karine Labadie, Benjamin Noel, Jean-Marc Aury, Steeve Thany, Emiliane Taillebois, Alison Cartereau, Anaïs Le Mauff, Claude L. Charvet, Clément Auger, Elise Courtot, Cédric Neveu and Olivier Plantard
    Citation: BMC Genomics 2022 23:463

    The Correction to this article has been published in BMC Genomics 2022 23:502

  13. Allorhizobium vitis (formerly named Agrobacterium vitis or Agrobacterium biovar 3) is the primary causative agent of crown gall disease of grapevine worldwide. We obtained and analyzed whole-genome sequences of d...

    Authors: Nemanja Kuzmanović, Enrico Biondi, Jörg Overmann, Joanna Puławska, Susanne Verbarg, Kornelia Smalla and Florent Lassalle
    Citation: BMC Genomics 2022 23:462
  14. Insect olfactory proteins can transmit chemical signals in the environment that serve as the basis for foraging, mate searching, predator avoidance and oviposition selection. Semanotus bifasciatus is an important...

    Authors: Han Li, Enhua Hao, Yini Li, Huan Yang, Piao Sun, Pengfei Lu and Haili Qiao
    Citation: BMC Genomics 2022 23:461
  15. Crossbreeding is an important way to improve production beef cattle performance. Pinan cattle is a new hybrid cattle obtained from crossing Piedmontese bulls with Nanyang cows. After more than 30 years of cros...

    Authors: Shunjin Zhang, Zhi Yao, Xinmiao Li, Zijing Zhang, Xian Liu, Peng Yang, Ningbo Chen, Xiaoting Xia, Shijie Lyu, Qiaoting Shi, Eryao Wang, Baorui Ru, Yu Jiang, Chuzhao Lei, Hong Chen and Yongzhen Huang
    Citation: BMC Genomics 2022 23:460
  16. Mucopolysaccharidosis IVA (Morquio syndrome A, MPS IVA) is an autosomal recessive lysosomal storage disorder caused due to biallelic variants in the N-acetylgalactoseamine-6-sulfate sulfatase (GALNS) gene. The mu...

    Authors: Harsh Sheth, Premal Naik, Maulin Shah, Riddhi Bhavsar, Aadhira Nair, Frenny Sheth and Jayesh Sheth
    Citation: BMC Genomics 2022 23:458
  17. Hu sheep and Tibetan sheep in China are characterized by fat tails and thin tails, respectively. Several transcriptomes have been conducted in different sheep breeds to identify the differentially expressed ge...

    Authors: Meilin Jin, Xiaojuan Fei, Taotao Li, Zengkui Lu, Mingxing Chu, Ran Di, Xiaoyun He, Xiangyu Wang and Caihong Wei
    Citation: BMC Genomics 2022 23:457
  18. This study examined the origin of present-day Lebanese using high-resolution HLA class I and class II allele and haplotype distributions. The study subjects comprised 152 unrelated individuals, and their HLA c...

    Authors: Wassim Y. Almawi, Rita Nemr, Ramzi R. Finan, F. Lisa Saldhana and Abdelhafidh Hajjej
    Citation: BMC Genomics 2022 23:456
  19. Congenital cytomegalovirus immunopathogenesis is largely unknown and multifactorial due to the complex interactions between viral, maternal, placental, and child factors. Polymorphisms in the HLA-E binding UL4015...

    Authors: David Tarragó, Irene González and Maria Francisca González-Escribano
    Citation: BMC Genomics 2022 23:455
  20. Disease emergence and production loss caused by cattle tick infestations have focused attention on genetic selection strategies to breed beef cattle with increased tick resistance. However, the mechanisms behi...

    Authors: Emily F. Mantilla Valdivieso, Elizabeth M. Ross, Ali Raza, Muhammad Noman Naseem, Muhammad Kamran, Ben J. Hayes, Nicholas N. Jonsson, Peter James and Ala E. Tabor
    Citation: BMC Genomics 2022 23:454
  21. Brassinosteroid (BR)- signaling kinase (BSK) is a critical family of receptor-like cytoplasmic kinase for BR signal transduction, which plays important roles in plant development, immunity, and abiotic stress ...

    Authors: Yang Li, Heng Zhang, Yongxue Zhang, Yanshuang Liu, Yueyue Li, Haodong Tian, Siyi Guo, Meihong Sun, Zhi Qin and Shaojun Dai
    Citation: BMC Genomics 2022 23:453
  22. An increasing number of long noncoding RNAs (lncRNAs) have been found to play important roles in sex differentiation and gonad development by regulating gene expression at the epigenetic, transcriptional and p...

    Authors: Zhi He, Lijuan Ye, Deying Yang, Zhijun Ma, Faqiang Deng, Zhide He, Jiaxiang Hu, Hongjun Chen, Li Zheng, Yong Pu, Yuanyuan Jiao, Qiqi Chen, Kuo Gao, Jinxin Xiong, Bolin Lai, Xiaobin Gu…
    Citation: BMC Genomics 2022 23:450
  23. Progressive CO2-induced ocean acidification (OA) impacts marine life in ways that are difficult to predict but are likely to become exacerbated over generations. Although marine fishes can balance acid–base homeo...

    Authors: Mishal Cohen-Rengifo, Morgane Danion, Anne-Alicia Gonzalez, Marie-Laure Bégout, Alexandre Cormier, Cyril Noël, Joëlle Cabon, Thomas Vitré, Felix C. Mark and David Mazurais
    Citation: BMC Genomics 2022 23:448
  24. Calcineurin-like Protein (CBL) and CBL interacting protein kinase (CIPK) play a key role in plant signal transduction and response to various environmental stimuli. Quinoa, as an important plant with high nutr...

    Authors: Zhu Xiaolin, Wang Baoqiang, Wang Xian and Wei Xiaohong
    Citation: BMC Genomics 2022 23:447
  25. The cnidarian myxozoan parasite Tetracapsuloides bryosalmonae causes chronic proliferative kidney disease (PKD) in salmonids. This parasite is a serious threat to wild and cultured salmonids. T. bryosalmonae unde...

    Authors: Arun Sudhagar, Mansour El-Matbouli and Gokhlesh Kumar
    Citation: BMC Genomics 2022 23:446
  26. The majority of Genome Wide Associate Study (GWAS) loci fall in the non-coding genome, making causal variants difficult to identify and study. We hypothesized that the regulatory features underlying causal var...

    Authors: Kim Lorenz, Christopher S. Thom, Sanjana Adurty and Benjamin F. Voight
    Citation: BMC Genomics 2022 23:444
  27. Breeding a mare until she is not fertile or even until her death is common in equine industry but the fertility decreases as the mare age increases. Embryo loss due to reduced embryo quality is partly accounta...

    Authors: Emilie Derisoud, Luc Jouneau, Cédric Dubois, Catherine Archilla, Yan Jaszczyszyn, Rachel Legendre, Nathalie Daniel, Nathalie Peynot, Michèle Dahirel, Juliette Auclair-Ronzaud, Laurence Wimel, Véronique Duranthon and Pascale Chavatte-Palmer
    Citation: BMC Genomics 2022 23:443
  28. The cultivation of edible mushroom is an emerging sector with a potential yet to be discovered. Unlike plants, it is a less developed agriculture where many studies are lacking to optimize the cultivation. In ...

    Authors: Maria Luisa Tello Martín, Rebeca Lavega, Jaime Carrasco Carrasco, Margarita Pérez, Antonio J. Pérez-Pulido, Michael Thon and Ernesto Pérez Benito
    Citation: BMC Genomics 2022 23:442
  29. Brassica species include important oil crops and vegetables in the world. The R2R3-MYB gene participates in a variety of plant functions, including the activation or inhibition of anthocyanin biosynthesis. Althou...

    Authors: Daozong Chen, Haidong Chen, Guoqiang Dai, Haimei Zhang, Yi Liu, Wenjie Shen, Bo Zhu, Cheng Cui and Chen Tan
    Citation: BMC Genomics 2022 23:441
  30. We introduce mirTarRnaSeq, an R/Bioconductor package for quantitative assessment of miRNA-mRNA relationships within sample cohorts. mirTarRnaSeq is a statistical package to explore predicted or pre-hypothesized m...

    Authors: Mercedeh Movassagh, Sarah U. Morton, Christine Hehnly, Jasmine Smith, Trang T. Doan, Rafael Irizarry, James R. Broach, Steven J. Schiff, Jeffrey A. Bailey and Joseph N. Paulson
    Citation: BMC Genomics 2022 23:439
  31. Elevated temperature and drought stress have substantial impacts on fruit quality, especially in terms of sugar metabolism and content. β-Amylase (BAM) plays a critical role in regulating jujube fruit sugar level...

    Authors: Yaping Ma, Yaru Han, Xuerui Feng, Handong Gao, Bing Cao and Lihua Song
    Citation: BMC Genomics 2022 23:438
  32. The pigmentation phenotype diversity is rich in domestic goats, and identification of the genetic loci affecting coat color in goats has long been of interest. Via the detections of selection signatures, a dup...

    Authors: Jiazhong Guo, Xueliang Sun, Ayi Mao, Haifeng Liu, Siyuan Zhan, Li Li, Tao Zhong, Linjie Wang, Jiaxue Cao, George E. Liu and Hongping Zhang
    Citation: BMC Genomics 2022 23:437
  33. Fusarium oxysporum f. sp. cucumerinum (FOC) is the causal agent of cucumber Fusarium wilt, which can cause extensive damages and productivity losses. Cucurbita ficifolia Bouché (Cucurbitaceae) is usually used as ...

    Authors: Junjun Xie, Yumei Ding, Ting Gao, Shuilian He, Kai Zhao, Xuehu Yang, Jie Zhang and Zhengan Yang
    Citation: BMC Genomics 2022 23(Suppl 1):436

    This article is part of a Supplement: Volume 23 Supplement 1

  34. Needle rust caused by the fungus Chrysomyxa rhododendri causes significant growth decline and increased mortality of young Norway spruce trees in subalpine forests. Extremely rare trees with enhanced resistance r...

    Authors: Carlos Trujillo-Moya, Andrea Ganthaler, Wolfgang Stöggl, Erwann Arc, Ilse Kranner, Silvio Schueler, Reinhard Ertl, Ana Espinosa-Ruiz, Maria Ángeles Martínez-Godoy, Jan-Peter George and Stefan Mayr
    Citation: BMC Genomics 2022 23:435
  35. Spatially-resolved transcriptomics has now enabled the quantification of high-throughput and transcriptome-wide gene expression in intact tissue while also retaining the spatial coordinates. Incorporating the ...

    Authors: Brenda Pardo, Abby Spangler, Lukas M. Weber, Stephanie C. Page, Stephanie C. Hicks, Andrew E. Jaffe, Keri Martinowich, Kristen R. Maynard and Leonardo Collado-Torres
    Citation: BMC Genomics 2022 23:434
  36. Shotgun metagenomics yields ever richer and larger data volumes on the complex communities living in diverse environments. Extracting deep insights from the raw reads heavily depends on the availability of fas...

    Authors: Felix Van der Jeugt, Rien Maertens, Aranka Steyaert, Pieter Verschaffelt, Caroline De Tender, Peter Dawyndt and Bart Mesuere
    Citation: BMC Genomics 2022 23:433
  37. The collection of circRNAs mostly focused on their sequence composition such as protein/miRNA binding motif, and/or regulatory elements such as internal ribosome entry site. However, less attention was paid to...

    Authors: Ya-Chi Lin, Yun-Chin Wang, Yueh-Chun Lee, Hui-Hsuan Lin, Kai-Li Chang, Yu-Chieh Tai and Kuei-Yang Hsiao
    Citation: BMC Genomics 2022 22(Suppl 5):921

    This article is part of a Supplement: Volume 22 Supplement 5

  38. The R2R3-MYB transcription factor is one of the largest gene families in plants and involved in the regulation of plant development, hormone signal transduction, biotic and abiotic stresses. Tobacco is one of ...

    Authors: Jiahan Yang, Binghui Zhang, Gang Gu, Jiazheng Yuan, Shaojun Shen, Liao Jin, Zhiqiang Lin, Jianfeng Lin and Xiaofang Xie
    Citation: BMC Genomics 2022 23:432
  39. Radiation proctitis (RP) is the most common complication of radiotherapy for pelvic tumor. Currently there is a lack of effective clinical treatment and its underlying mechanism is poorly understood. In this s...

    Authors: Qingzhi Zeng, Jingyang Cheng, Haiyong Wu, Wenfeng Liang and Yanmei Cui
    Citation: BMC Genomics 2022 23:431

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