Figure 3

Breakpoint density is higher in heavy isochors. Intergenic breakpoint density estimated using model M1 versus GC content. Data points were obtained by (i) ordering 50 kb windows according to their GC content, (ii) grouping them into classes of equal number of intergenic breakpoints and (iii) computing intergenic breakpoint density and average GC content over each class. Vertical bars represent the standard deviations (see Methods); horizontal bars represent the ranges of GC content over each class.