Transcriptional adaptations following exercise in Thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy

Table 1 Genes ≥ +1.5-fold (up-regulated) differential expression immediately post-exercise compared to pre-exercise levels.

Gene Symbol	Gene Name	GenBank ID	Fold change	P	adj P	A nnotation
HSPA1A	Heat shock 70 kDa protein 1A	CX602571	3.11	1.50E-07	0.001	EquCab
HSPA1A	Heat shock 70 kDa protein 1A	CX600510	2.15	2.42E-05	0.080	EquCab
FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	CX597113	2.13	0.004	0.997	chr24:20,679,377-20,681,089
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase	CX594334	1.96	4.71E-06	0.023	chr29:27,672,694-27,678,314
FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	CX604427	1.87	0.003	0.997	H. Sapien
FOS	v-fos FBJ murine osteosarcoma viral oncogene homolog	CX592361	1.59	0.039	0.997	H. Sapien
EGR1	early growth response 1	CX602573	1.55	0.014	0.997	H. Sapien

The gene names provided are either HUGO approved or Equus caballus specific.
Adj P is the P-value following adjustment for multiple testing.
Predicted gene annotations were assigned to unannotated probes of interest based on the gene located closest to the probe and homology to mammalian genes, chromosomal locations are provided for these genes.

ISSN: 1471-2164