Table 3 Validation of the added genes based on different information sources. The P-value is calculated using hyper-geometric distribution.
From: Computational prediction of the osmoregulation network in Synechococcus sp. WH8102
Methods | Number of recruited genes | Differentially-expressed genes (false discovery rate ≤ 0.01) | P-value |
|---|---|---|---|
Initial model | 27 | 9 | 5.24 × 10-7 |
Operon | 24 | 4 | 1.44 × 10-2 |
Protein-protein interactions | 16 | 1 | 0.48 |
Regulon prediction | 41 | 3 | 0.23 |
Phylogenetic profile | 13 | 1 | 0.42 |
Expanded model | 114 | 15 | 3.44 × 10-5 |