Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift?

Table 1 Vaccination history of different countries

Country	Period	Comment	Year of Isolation	Number of strains
Netherlands	NV	vaccine strains		2
Netherlands	N1	pre-vaccination period	1949-1953	11
Netherlands	N2	Early post vaccine WCV	1953-1964	5
Netherlands	N3	late post vaccine WCV	1965-1975	6
Netherlands	N4	vaccine dose reduction period	1976-1984	16
Netherlands	N5	post vaccine dose reduction period	1985-1992	15
Netherlands	N6	Epidemic	1993-2004	31
Netherlands	N7	Early post ACV	2005-2008	18
Sweden	Sw1	Post WCV	1953-1978	5
Sweden	Sw2	Vaccine free period	1979-1996	7
Sweden	Sw3	Post ACV	1997-2008	8
Japan	J1	Post WCV	1949-1981	1
Japan	J2	Post ACV	1982-2008	7
Australia	A1	Post WCV	1950-1998	15
Australia	A2	Post ACV	1999-2008	-
Senegal	Se1	Vaccine free period	until 1987	-
Senegal	Se2	Early post WCV	1988-2008	10
Kenya	K1	Vaccine free period	until 2008	13
		Reference strain, Tohama I		1

ISSN: 1471-2164