overview of distribution of secretome proteins in LaCOGs. The central pie depicts the distribution of secretome proteins in LaCOGs according to their functional classes. The percentage was calculated as the number of proteins in the category divided by the total of 3357 secretome proteins that were clustered into LaCOGs. The number of LaCOGs in each category is listed in the pie chart legend behind the name of the functional class. The separate yellow-red-green piecharts for each functional class represents the distribution of this LaCOG in the LAB genomes, i.e. ubiquitous, .species/strain-specific, or variable.