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Table 1 Comparison of genes significantly induced following drug treatment with in-house curated lists of genes.

From: Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope

Entity list Genes in entity list present on microarray Vancomycin-induced (744 genes) Bacitracin-induced (481 genes) Moenomycin-induced (616 genes) Induced by all (243 genes)
   Genes in entity list matched with induced genes P-Value Genes in entity list matched with induced genes P-Value Genes in entity list matched with induced genes P-Value Genes in entity list matched with induced genes P-Value
SigB regulon 87 39 <1E-33 33 <1E-34 42 <1E-10 29 <1E-11
Heat shock regulon 119 51 <1E-33 27 3.13E-09 43 <1E-10 26 <1E-11
ppGpp-induced genes 98 50 1.46E-25 42 <1E-34 28 1.48E-09 20 <1E-11
Gas vesicle 1 8 8 7.71E-09 7 2.81E-08 7 1.58E-07 7 2.33E-10
SigE operon 4 4 8.87E-05 4 1.54E-05 4 4.16E-05 4 9.92E-07
Ectoine biosynthesis 4 4 8.87E-05 4 1.54E-05 4 4.16E-05 4 9.92E-07
CDA 47* 39 1.96E-32 35 6.87E-33 11 0.00100 11 1.67E-07
Peptidoglycan biosynthesis (external) 16 8 4.87E-05 5 0.00234 5 0.00686 4 0.001335
Sigma factors 64 14 0.00283 14 3.23E-05 11 0.01230 8 8.76E-04
Red 23* 23 3.83E-24 9 5.25E-06     
Wbl 10 5 0.00142 3 0.02123     
SsgA like 8 4 0.00450 3 0.01089     
Cell wall hydrolyases 57    9 0.00856 14 1.23E-04   
ppGpp-repressed genes 189      28 0.00111   
Resuscitation-promoting factors 7      5 6.09E-05   
Gly Ser Thr biosynthesis 35      9 0.00140   
NRPS type II FAS 10      4 0.00589   
Amino acid metabolism 184      24 0.01225   
SigR regulon 26      6 0.01517   
Hopanoids 13      4 0.01651   
Amino acid transport 34      7 0.01675 4 0.0217
Methionine biosynthesis 9      3 0.03018   
Lysine bioysnhtesis 16      4 0.03468   
Val Leu Ile biosynthesis 25      5 0.04587   
Sensor kinase 48    10 6.56E-04     
Response regulators 94    11 0.0329     
Zur regulon 22 19 5.50E-17       
van cluster genes 7 7 8.00E-08       
Coelibactin 13 7 8.11E-05       
  1. *indicates the number of probe sets rather than the number of genes.