From: Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope
Entity list | Genes in entity list present on microarray | Vancomycin-induced (744 genes) | Bacitracin-induced (481 genes) | Moenomycin-induced (616 genes) | Induced by all (243 genes) | ||||
---|---|---|---|---|---|---|---|---|---|
 |  | Genes in entity list matched with induced genes | P-Value | Genes in entity list matched with induced genes | P-Value | Genes in entity list matched with induced genes | P-Value | Genes in entity list matched with induced genes | P-Value |
SigB regulon | 87 | 39 | <1E-33 | 33 | <1E-34 | 42 | <1E-10 | 29 | <1E-11 |
Heat shock regulon | 119 | 51 | <1E-33 | 27 | 3.13E-09 | 43 | <1E-10 | 26 | <1E-11 |
ppGpp-induced genes | 98 | 50 | 1.46E-25 | 42 | <1E-34 | 28 | 1.48E-09 | 20 | <1E-11 |
Gas vesicle 1 | 8 | 8 | 7.71E-09 | 7 | 2.81E-08 | 7 | 1.58E-07 | 7 | 2.33E-10 |
SigE operon | 4 | 4 | 8.87E-05 | 4 | 1.54E-05 | 4 | 4.16E-05 | 4 | 9.92E-07 |
Ectoine biosynthesis | 4 | 4 | 8.87E-05 | 4 | 1.54E-05 | 4 | 4.16E-05 | 4 | 9.92E-07 |
CDA | 47* | 39 | 1.96E-32 | 35 | 6.87E-33 | 11 | 0.00100 | 11 | 1.67E-07 |
Peptidoglycan biosynthesis (external) | 16 | 8 | 4.87E-05 | 5 | 0.00234 | 5 | 0.00686 | 4 | 0.001335 |
Sigma factors | 64 | 14 | 0.00283 | 14 | 3.23E-05 | 11 | 0.01230 | 8 | 8.76E-04 |
Red | 23* | 23 | 3.83E-24 | 9 | 5.25E-06 | Â | Â | Â | Â |
Wbl | 10 | 5 | 0.00142 | 3 | 0.02123 | Â | Â | Â | Â |
SsgA like | 8 | 4 | 0.00450 | 3 | 0.01089 | Â | Â | Â | Â |
Cell wall hydrolyases | 57 | Â | Â | 9 | 0.00856 | 14 | 1.23E-04 | Â | Â |
ppGpp-repressed genes | 189 | Â | Â | Â | Â | 28 | 0.00111 | Â | Â |
Resuscitation-promoting factors | 7 | Â | Â | Â | Â | 5 | 6.09E-05 | Â | Â |
Gly Ser Thr biosynthesis | 35 | Â | Â | Â | Â | 9 | 0.00140 | Â | Â |
NRPS type II FAS | 10 | Â | Â | Â | Â | 4 | 0.00589 | Â | Â |
Amino acid metabolism | 184 | Â | Â | Â | Â | 24 | 0.01225 | Â | Â |
SigR regulon | 26 | Â | Â | Â | Â | 6 | 0.01517 | Â | Â |
Hopanoids | 13 | Â | Â | Â | Â | 4 | 0.01651 | Â | Â |
Amino acid transport | 34 | Â | Â | Â | Â | 7 | 0.01675 | 4 | 0.0217 |
Methionine biosynthesis | 9 | Â | Â | Â | Â | 3 | 0.03018 | Â | Â |
Lysine bioysnhtesis | 16 | Â | Â | Â | Â | 4 | 0.03468 | Â | Â |
Val Leu Ile biosynthesis | 25 | Â | Â | Â | Â | 5 | 0.04587 | Â | Â |
Sensor kinase | 48 | Â | Â | 10 | 6.56E-04 | Â | Â | Â | Â |
Response regulators | 94 | Â | Â | 11 | 0.0329 | Â | Â | Â | Â |
Zur regulon | 22 | 19 | 5.50E-17 | Â | Â | Â | Â | Â | Â |
van cluster genes | 7 | 7 | 8.00E-08 | Â | Â | Â | Â | Â | Â |
Coelibactin | 13 | 7 | 8.11E-05 | Â | Â | Â | Â | Â | Â |