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Table 6 "Top 20 known genes" up-regulated in the group fasted without scales (STWS) in relation to the control (N) on day 3.

From: Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus

Clone

LogFold

adj P-val

Accession Number

Gene Identification

Putative function

SAPD06461

3.396

0.002

Q9BY76

Angiopoietin-related protein 4 precursor

Inhibition of proliferation, migration and tubule formation of endothelial cells. May exert a protective action on endothelial cells via endocrine action.

SAPD22431

3.138

0.031

IPI00015568

Homolog of Homo sapiens Protein KIAA0711

Transcriptional repression.

SAPD09760

2.742

0.007

IPI00298828

Homolog of Homo sapiens Beta-2-glycoprotein I precursor

Blood coagulation and immune response.

SAPD03340

2.530

0.039

Q6P0E4

Type I cytokeratin, enveloping layer

Structural protein.

SAPD20440

2.519

0.001

NP_065109

Patatin-like phospholipase domain containing 2

Energy homeostasis. May play a role in response of organism to starvation, enhancing hydrolysis of triglycerides etc to be used in situations of energy depletion.

SAPD22329

2.469

0.000

Q8TAV3

Cytochrome P450 2W1 (CYPIIW1)

Oxidative degradation and detoxification.

SAPD02465

2.422

0.016

Q6P2U4

Homolog of Brachydanio rerio Sulfotransferase family, cytosolic sulfotransferase 2

Metabolic action. Increases water solubility of compounds plus bioactivation of metabolites.

SAPD20351

2.364

0.006

IPI00298828

Homolog of Homo sapiens Beta-2-glycoprotein I precursor

Blood coagulation and immune response.

SAPD25836

2.176

0.017

Q9Y3D2

Methionine-R-sulfoxide reductase B2

Antioxidant repair.

SAPD24645

1.841

0.004

P00480

Ornithine carbamoyltransferase, mitochondrial precursor

Amino acid biosynthesis.

SAPD10144

1.793

0.033

Q15119

Pyruvate dehydrogenase kinase isoform 2

Regulation of glucose metabolism.

SAPD23209

1.724

0.004

O43175

D-3-phosphoglycerate dehydrogenase (3-PGDH)

Amino acid biosynthesis, cell growth and differentiation, metabolic development and CNS function.

SAPD22251

1.705

0.013

Q6PGQ7

Protein aurora borealis HsBora

Cell division and mitosis.

SAPD23370

1.704

0.012

Q9Y5Y7

Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor

Facilitates cell migration during wound healing and inflamation.

SAPD14269

1.702

0.017

Q9BUX1

Cation transport regulator-like protein 1

Potential component of the unfolded protein response.

SAPD25026

1.689

0.007

NP_001003640

Hypothetical protein LOC445246

RNA binding. Plectrin domain present in some forms ofcytoskeletal muscle and ribosomal S10 protein (translation).

SAPD13849

1.589

0.005

Q9H7X7

Rab-like protein 5

Regulator of haematopoietic cells with roles in cell growth, survival, differentiation, cytokine production, chemotaxis, vesicle trafficking and phagocytosis.

SAPD16979

1.496

0.003

NP_998427

Eukaryotic translation initiation factor 5A

Translation.

SAPD19571

1.384

0.016

O60566

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Control of the cell cycle.

SAPD21410

1.342

0.025

Q8WWL7

G2/mitotic-specific cyclin-B3

Control of the cell cycle.

  1. The "Top 20 known genes" were taken from 37 transcripts of which 17 showed no match to genes of known function. Putative functionality was assigned via BLAST sequence similarity searching. All matches are in excess of 1.0 e-10. Table definitions are the same as for Table 4.