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Table 7 "Top 20 Known genes" up-regulated in the group fasted without scales (STWS) in relation to fasted group (ST) on day 3.

From: Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus

Clone

LogFold

adj P-val

Acc. Number

Gene Identification

Putative function

SAPD11916

4.104

0.009

IPI00005781

Splice Isoform A of Arachidonate 15-lipoxygenase, type II

Mediates allergic response. Restricts cell cycle progression.

SAPD06895

3.415

0.002

Q9Y617

Phosphoserine aminotransferase

Amino acid biosynthesis.

SAPD18045

3.355

0.000

Q02241

Kinesin-like protein KIF23

Mitosis and cell cycle.

SAPD00860

3.308

0.000

P14635

G2/mitotic-specific cyclin-B1

Control of the cell cycle at G2/M transition.

SAPD03340

3.298

0.006

Q6P0E4

Type I cytokeratin, enveloping layer

Structural protein.

SAPD11351

3.260

0.003

Q07426

Homolog of Carassius auratus Keratin

Structural protein.

SAPD04986

3.251

0.000

IPI00027157

Homolog of Homo sapiens CENP-F kinetochore protein

Involved in the cell cycle.

SAPD17903

3.160

0.000

IPI00412862

Homolog of Homo sapiens M-phase phosphoprotein 1

Involved in the cell cycle.

SAPD25367

3.039

0.001

Q5XFY1

Macrophage stimulating 1 Hepatocyte growth factor-like

Involved in cell proliferation and differentiation and tissue repair. Epidermal wound healing.

SAPD17933

3.017

0.000

Q15125

3-beta-hydroxysteroid-Delta8,Delta7-isomerase

Involved in sterol contribution to bone development.

SAPD23466

3.013

0.014

XP_641063.1

Hypothetical protein DDBDRAFT_0206057

Ubiquitin: multifunctional protein involved in cell cycle regulation, DNA repair, protein degradation, regulation of transcription, apoptosis and immune response.

SAPD20573

2.987

0.000

Q96EA4

Coiled-coil domain-containing protein 99

Involved in cell divsion via localisation of dyein and dynactin to kinetochore.

SAPD14492

2.975

0.001

P33981

Dual specificity protein kinase TTK

Associated with cell proliferation. Essential for the alignment of chromosomes by enhancing AURKB activity at centromere for mitotic check point.

SAPD09826

2.967

0.000

Q5T113

Uncharacterized protein C9orf156 Nef-associated protein 1

Hydrolyses acyl Co-A thioesters in vitro. Physiological function is unknown.

SAPD18060

2.898

0.001

NP_060445

Zwilch

Essential component of the mitotic check point. Required for dyein-dynactin and MAD1/MAD2 complexes onto kinetochores.

SAPD22251

2.847

0.000

Q6PGQ7

Protein aurora borealis HsBora

Cell division and mitosis.

SAPD11258

2.840

0.000

P29218

Inositol monophosphatase

Cell signalling.

SAPD18820

2.778

0.003

Q12905

Interleukin enhancer-binding factor 2

May regulate transcription of IL2 during T-cell activation: immune response. Functions as a ds RNA binding protein to promote autoimmunity.

SAPD23209

2.755

0.000

O43175

D-3-phosphoglycerate dehydrogenase 3-PGDH

Amino acid biosynthesis, cell growth and differentiation, metabolic development and CNS function.

SAPD18364

2.749

0.000

Q1LV50

Centromere protein P CENP-P

Component of the centromeric complex, involved in mitotic progression and chromosome segregation.

  1. The "Top 20 known genes" were taken from 27 transcripts of which 7 showed no match to genes of known function. Putative functionality was assigned via BLAST sequence similarity searching. All matches are in excess of 1.0 e-10. Table definitions are the same as for Table 4.