Table 2 The 10 most up- and down-regulated genes in DF-1 cells as determined by Ingenuity Pathway Analysis software

AB196971

APCDD1

adenomatosis polyposis coli down-regulated 1

4.75

4.68 × 10^-8

AJ131110

TWIST2

twist homolog 2 (Drosophila)

4.61

3.93 × 10^-9

BX936211

TMEM116

transmembrane protein 116

4.26

9.58 × 10^-10

S64689

MYH6

myosin, heavy chain 6, cardiac muscle, alpha

3.52

4.92 × 10^-6

AJ851540

CARD11

caspase recruitment domain family, member 11

3.51

1.66 × 10^-8

BX932923

PLEK2

pleckstrin 2

3.47

2.63 × 10^-8

CR523499

OSGIN1

oxidative stress induced growth inhibitor 1

3.43

5.04 × 10^-9

DQ129668

COLEC10

collectin sub-family member 10 (C-type lectin)

3.19

1.81 × 10^-7

BX933215

SOCS1

suppressor of cytokine signaling 1

3.05

3.63 × 10^-7

CR407099

VPS13B

vacuolar protein sorting 13 homolog B (yeast)

3.03

3.44 × 10^-6

The 10 most down-regulated genes

ID

Symbol

Entrez Gene Name

Log Ratio

p-value

X59284

NOV

nephroblastoma overexpressed gene

-8.40

3.11 × 10^-9

AJ719388

SLC25A4

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

-7.69

1.22 × 10^-10

Y138247

CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

-7.68

2.75 × 10^-10

X80503

ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

-7.26

4.67 × 10^-9

M64990

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

-6.78

1.11 × 10^-10

X935556

CTHRC1

collagen triple helix repeat containing 1

-6.78

3.20 × 10^-8

M68514

EPHA3

ephrin receptor A3

-6.73

5.89 × 10^-9

AJ719946

MANSC1

MANSC domain containing 1

-6.65

5.66 × 10^-8

AJ251273

CCK

cholecystokinin

-6.63

1.27 × 10-11

Y049705

MAB21L1

mab-21-like 1 (C. elegans)

-6.44

2.26 × 10^-10