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Table 2 The 10 most up- and down-regulated genes in DF-1 cells as determined by Ingenuity Pathway Analysis software

From: Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell line

The 10 most up-regulated genes
ID Symbol Entrez Gene Name Log Ratio p-value
AB196971 APCDD1 adenomatosis polyposis coli down-regulated 1 4.75 4.68 × 10-8
AJ131110 TWIST2 twist homolog 2 (Drosophila) 4.61 3.93 × 10-9
BX936211 TMEM116 transmembrane protein 116 4.26 9.58 × 10-10
S64689 MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.52 4.92 × 10-6
AJ851540 CARD11 caspase recruitment domain family, member 11 3.51 1.66 × 10-8
BX932923 PLEK2 pleckstrin 2 3.47 2.63 × 10-8
CR523499 OSGIN1 oxidative stress induced growth inhibitor 1 3.43 5.04 × 10-9
DQ129668 COLEC10 collectin sub-family member 10 (C-type lectin) 3.19 1.81 × 10-7
BX933215 SOCS1 suppressor of cytokine signaling 1 3.05 3.63 × 10-7
CR407099 VPS13B vacuolar protein sorting 13 homolog B (yeast) 3.03 3.44 × 10-6
The 10 most down-regulated genes
ID Symbol Entrez Gene Name Log Ratio p-value
X59284 NOV nephroblastoma overexpressed gene -8.40 3.11 × 10-9
AJ719388 SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -7.69 1.22 × 10-10
Y138247 CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) -7.68 2.75 × 10-10
X80503 ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -7.26 4.67 × 10-9
M64990 PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -6.78 1.11 × 10-10
X935556 CTHRC1 collagen triple helix repeat containing 1 -6.78 3.20 × 10-8
M68514 EPHA3 ephrin receptor A3 -6.73 5.89 × 10-9
AJ719946 MANSC1 MANSC domain containing 1 -6.65 5.66 × 10-8
AJ251273 CCK cholecystokinin -6.63 1.27 × 10-11
Y049705 MAB21L1 mab-21-like 1 (C. elegans) -6.44 2.26 × 10-10
  1. Fold change (FC) values were indicated by log2. The highly differentially expressed genes were sorted. All genes were matched and verified with UniGene function of NCBI database.