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Table 1 Selection of candidate hypothetical genes families conserved in Arabidopsis (AT) and prokaryotes for in silico functional predictions and potential experimental verification – an overview.

From: Synergistic use of plant-prokaryote comparative genomics for functional annotations

AT gene families in this study AT genes (and families) screened AT genes with prokaryote homolog(s) AT genes selected for in silico analysis Gene families connected to metabolic areas Families with specific hypotheses formulated Families experimentally tested in this study Families with validated functions -
        in this study by others
Singletons 3,625 666 (18.4%) 178 42 21 10 3 5
Duplets 3,204 (1,602 x2) 909 (28.4%) 190 21 13 7 3 2
Triplets a 2,421 (807 x3) 849 (35.0%) 262 14 6 3 2 3
      (+1)b (+1)b (+1)b  
Total 9,250 (6,034) 2,325 (25.1%) 630 78 41 21 c 9 10
  1. a Includes several Arabidopsis gene families with 4 or more paralogs
  2. b One candidate was not in the Arabidopsis set (number 4 in Table 2).
  3. c Includes 9 families with functions experimentally validated, 4 invalidated, and 8 for which experimental validation is currently in progress (see Table 2 and Table 3 for details).