Table 7 SNVs with |ΔDS |>0.04 in Q1, Q2 and disease liability
From: Changes in predicted protein disorder tendency may contribute to disease risk
trait | SNV name | Gene name | AA changes | ΔDS | Major Allele Score |
|---|---|---|---|---|---|
Q1 | C19S4815 | HIF3A | R→C | -0.10 | 0.81 |
Q1 | C4S1879 | KDR | V →M | 0.04 | 0.11 |
Q2 | C9S377 | VLDLR | W→ C | 0.18 | 0.51 |
Q2 | C9S444 | VLDLR | D→ Y | -0.16 | 0.36 |
Q2 | C10S3050 | SIRT1 | P → L | -0.16 | 0.33 |
Q2 | C8S476 | LPL | I→S | 0.15 | 0.17 |
Q2 | C8S530 | LPL | V→ G | 0.13 | 0.32 |
Q2 | C6S5446 | VNN3 | V→ I | -0.05 | 0.44 |
Q2 | C8S442 | LPL | D→N | -0.04 | 0.29 |
disease Liability | C17S4581 | PRKCA | V → E | 0.19 | 0.37 |
disease Liability | C18S2492 | PIK3C3 | V→ G | 0.13 | 0.32 |
disease Liability | C1S9266 | PIK3C2B | S → F | -0.13 | 0.77 |
disease Liability | C8S900 | PTK2B | S → L | -0.13 | 0.38 |
disease Liability | C2S2307 | BCL2L11 | M → R | 0.07 | 0.44 |
disease Liability | C1S9267 | PIK3C2B | P → L | -0.06 | 0.83 |