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Table 2 Illumina® whole-genome re-sequencing - Confirmed and High-Confidence Mutations in AS-30CQ

From: Quantitative genome re-sequencing defines multiple mutations conferring chloroquine resistance in rodent malaria

Chr   Nucleotide number WTSI AS-30CQ Quality Score Mutation Gene (abbrev) Nearest Gene P. falciparum orthologue
  POINT MUTATIONS        
2   216,954 C A 99 V2728F PCHAS_020720   PFA0220w
3   70,553 G T 99 T707N PCHAS_030200   none
3   474,123 C A 99 T719 PCHAS_031370   PFB0675w
7   994,546 G A 99 S106N PCHAS_072830   PFD0830w
10   634,932 T C 99 Y162H PCHAS_101550   PF14_0279
11   996,332 G T 99 A173E PCHAS_112780   PFF1430c
14   936,945 T G 92    PCHAS_142600 PF08_0081
  DELETIONS        
  Start (nucleotide number) Finish (nucleotide number)        
5 683,724 684,989      PCHAS_051920   none
7 876,909 876,914       PCHAS_072420 PF08_0067
  1. Summary of the high confidence mutations proposed in clone AS-30CQ (see Additional File 1). Read depth and quality scores fro mutations were according to SSAHA2. Start and Finish nucleotides for deletions are approximate only.