Table 1 Twenty-five common up-regulated genes of B. pseudomallei during intracellular growth in host macrophages relative to in vitro growth

BPSL0184

Putative rod shape-determining protein

23.83

15.31

12.69

12.06

BPSL0842

Benzoylformate decarboxylase

70.27

31.78

27.64

20.64

BPSL0886

Hypothetical protein

12.29

8.36

6.56

5.20

BPSL1067

Hypothetical protein

8.39

5.15

6.75

6.27

BPSL1771

Cobalamin biosynthesis protein CbiG

25.36

16.66

15.21

15.76

BPSL1817

Putative lipoprotein

30.07

14.11

12.67

11.33

BPSL1902

Hypothetical protein

37.91

18.81

12.46

8.39

BPSL2759

Putative short-chain dehydrogenase

16.54

8.31

5.93

5.61

BPSL2945

Allantoicase

27.90

9.57

8.83

7.41

BPSL3354

Putative cytochrome

18.66

11.70

8.64

7.62

BPSS0140

Sugar ABC transport system, lipoprotein

7.80

16.62

13.56

13.94

BPSS0142 *

Sugar ABC transport system, ATP-binding protein

4.62

10.04

11.34

18.79

BPSS0143

ROK family transcriptional regulator

4.78

9.97

11.80

18.64

BPSS0404

Methylamine utilization protein

49.46

36.31

30.14

23.42

BPSS0433

Hypothetical protein

11.87

5.84

7.70

10.59

BPSS0529

Lipoprotein

26.49

19.04

14.10

10.68

BPSS1279

Threonine dehydratase

17.47

11.84

10.80

11.03

BPSS1498 *

tssD, type VI secretion system Hcp protein

7.38

93.61

130.11

181.92

BPSS1499

tssE, type VI secretion system lysozyme

4.72

58.87

99.06

160.21

BPSS1505

tagB, type VI secretion system hypothetical protein

6.49

14.01

18.40

27.97

BPSS1508

tssJ, type VI secretion system lipoprotein

5.04

6.27

8.17

9.88

BPSS1728 *

Secretion/activator protein

3.00

23.60

29.33

24.54

BPSS1892

catA, catechol 1,2-dioxygenase

7.76

19.46

16.64

16.53

BPSS1893

catC, muconolactone delta-isomerase

10.57

9.30

7.33

6.30

BPSS2276

LysR family regulatory protein

59.21

41.83

26.33

19.45