Table 2 Gene function enrichment analysis of B. pseudomallei common up-regulated and down-regulated genes throughout growth within host macrophages

Up-regulated genes

Benzoate degradation via hydroxylation

3

29

3.33 × 10^-2

Down-regulated genes

Amino sugar and nucleotide sugar metabolism

22

39

7.98 × 10^-10

Bacterial chemotaxis

23

46

2.65 × 10^-9

Lipopolysaccharide biosynthesis

13

24

2.36 × 10^-5

Peptidoglycan biosynthesis

11

24

7.93 × 10^-4

Flagella assembly

11

38

2.72 × 10^-2

Alanine, aspartate and glutamate metabolism

15

32

2.41 × 10^-5

Fatty acid biosynthesis

9

21

6.33 × 10^-3

Two-component system

30

104

3.68 × 10^-6

Glycolysis/gluconeogenesis

11

36

1.81 × 10^-2

Oxidative phosphorylation

15

60

1.55 × 10^-2