From: Burkholderia pseudomallei transcriptional adaptation in macrophages
Functional class or pathway | No. of genes regulated | No. of genes in genome | Significance (p- value) |
---|---|---|---|
Up-regulated genes | Â | Â | Â |
Benzoate degradation via hydroxylation | 3 | 29 | 3.33 × 10-2 |
Down-regulated genes | Â | Â | Â |
Amino sugar and nucleotide sugar metabolism | 22 | 39 | 7.98 × 10-10 |
Bacterial chemotaxis | 23 | 46 | 2.65 × 10-9 |
Lipopolysaccharide biosynthesis | 13 | 24 | 2.36 × 10-5 |
Peptidoglycan biosynthesis | 11 | 24 | 7.93 × 10-4 |
Flagella assembly | 11 | 38 | 2.72 × 10-2 |
Alanine, aspartate and glutamate metabolism | 15 | 32 | 2.41 × 10-5 |
Fatty acid biosynthesis | 9 | 21 | 6.33 × 10-3 |
Two-component system | 30 | 104 | 3.68 × 10-6 |
Glycolysis/gluconeogenesis | 11 | 36 | 1.81 × 10-2 |
Oxidative phosphorylation | 15 | 60 | 1.55 × 10-2 |