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Figure 3 | BMC Genomics

Figure 3

From: Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

Figure 3

Summary of candidate mutations regulating various pathogenic phenotypes in SAMP strains. Described mutations except for Ogg1 p.R304W and Mbd4 p.D129N are SAMP-specific novel non-synonymous mutations that were identified in the present study. Although Ogg1 p.R304W and Mbd4 p.D129N were detected in other strains, they would be involved in the susceptibility of diseases via defects in DNA repair.

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BMC Genomics

ISSN: 1471-2164

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