Figure 4

Central metabolic pathways of Acetobacter pasteurianus 386B. (1) Phosphoglucomutase (APA386B_513); (2) glucose-6-phosphate isomerase (APA386B_1153); (3) fructose-1,6-biphosphatase I (APA386B_993); (4) fructose-biphosphate aldolase, class I (APA386B_1752); (5) triose-phosphate isomerase (APA386B_2746); (6) glyceraldehyde-3-phosphate dehydrogenase (APA386B_1520); (7) phosphoglycerate kinase (APA386B_1519); (8) phosphoglycerate mutase (APA386B_1895 and APA386B_2495); (9) enolase (APA386B_2618); (10) pyruvate kinase (APA386B_2108); (11) pyruvate-phosphate dikinase (APA386B_814); (12) phosphoenolpyruvate carboxylase (APA386B_587); (13) fructokinase (APA386B_356); (14) PQQ-dependent glucose dehydrogenase (APA386B_2133 - APA386B_2134); (15) gluconolactonase (APA386B_2110); (16) gluconate kinase (APA386B_1158); (17) phosphogluconate dehydrogenase (APA386B_1154); (18) ribulose-phosphate 3-epimerase (APA386B_2378); (19) ribose-5-phosphate isomerase A (APA386B_1157); (20) transketolase (APA386B_1152 and APA386B_1521); (21) transaldolase (APA386B_1153) (22) glucose-6-phosphate dehydrogenase (APA386B_729); (23) 6-phosphogluconolactonase (APA386B_1156); (24) glycerol kinase (Apa396B_92); (25) glycerol-3-phosphate dehydrogenase (APA386B_1931 and APA386B_94); (26) pyruvaldehyde oxidoreductase (APA386B_1946); (27) lactoylgluthathione lyase (APA386B_2164 and APA386B_1276); (28) hydroxyacylglutathione hydrolase (APA386B_2280); (29) lactate dehydrogenase (APA386B_910 and APA386B_1053); (30) pyruvate dehydrogenase E1 (APA386B_2083 - APA386B_2084 and APA386B_2737 - APA386B_2738); (31) pyruvate dehydrogenase E2 (APA386B_2085 and APA386B_2736); (32) dihydrolipoamide dehydrogenase (APA386B_2735 and APA386B_2271); (33) pyruvate decarboxylase (APA386B_1186); (34) alcohol dehydrogenase (APA386B_1507, APA386B_2362, and APA386B_496); (35) aldehyde dehydrogenase (APA386B_909); (36) acetyl-CoA synthetase (APA386B_1843 and APA386B_2214); (37) acetate kinase (APA386B_335); (38) phosphate acetyltransferase (APA386B_336); (39) malate dehydrogenase (APA386B_1600); (40) aconitate hydratase 1 (APA386B_1323); (41) NAD⁺-dependent isocitrate dehydrogenase (APA386B_2558); (42) NADP⁺-dependent isocitrate dehydrogenase (APA386B_2121); (43) 2-oxoglutarate dehydrogenase E1 (APA386B_2269); (44) 2-oxoglutarate dehydrogenase E2 (APA386B_2270); (45) fumarate reductase/succinate dehydrogenase (APA386B_1513 - APA386B_1516); (46) fumarate hydratase (APA386B_321 and APA386B_1305); (47) malate:quinone oxidoreductase (APA386B_2675); (48) citrate synthase (APA386B_2584); (49) succinyl-CoA:acetate CoA transferase (APA386B_2589); (50) glucosamine-6-phosphate isomerase (APA386B_546); (51) N-acetylglucosamine-6-phosphate deacetylase (APA386B_1531); (52) polyol oxidoreductase (APA386B_2545).