miRNA and miRNA target genes in copy number variations occurring in individuals with intellectual disability

BMC Genomics

Table 1 Comparison of the number of miRNAs in different CNV subgroups

CNV category	No. of CNVs	No. of CNVRs	Size of total CNVRs (Mb)	Average size of CNVRs (Mb)	miRNA
CNV category	No. of CNVs	No. of CNVRs	Size of total CNVRs (Mb)	Average size of CNVRs (Mb)	Total No. (#)	Average miRNA/Mb	#/CNVR	Weighted median No.
*De novo*	24	22	70.5	3.21	84	1.20	3.8	0.6^a
Familial	46	46	29.5	3.34	14	0.47	0.3	0^b
Common from case s	216	210	105.2	0.64	67	0.64	0.3	0^b
Common from control cohort	67	61	34.1	0.56	30	0.88	0.5	0^b
Pathogenic from DECIPHER	35	30	100.1	0.50	90	0.90	3.0	0.8^a

^a,b:Significant difference was found between data a and b (P < 0.05) (a Wilcoxon signed-rank test).

ISSN: 1471-2164