Table 2 Genes downregulated under iron-limiting conditions and in the fur mutant
From: Global transcriptional response of Caulobacter crescentus to iron availability
Gene CB15 | Gene NA1000 | Predicted function | Fold changea | |
|---|---|---|---|---|
WT DP/WT Fe | ∆fur Fe/WT Fe | |||
Transport | ||||
CC_0925 | CCNA_00974 | OAR protein precursor (OmpA-like protein) | −8.22 | −2.74 |
CC_0991 | CCNA_01042 | TonB-dependent receptor | −2.47 | −2.27 |
CC_1099 | CCNA_01155 | TonB-dependent outer membrane receptor | −2.22 | −2.06 |
CC_2485 | CCNA_02570 | Transporter (Major Facilitator Superfamily) | −2.49 | −3.24 |
CC_2486 | CCNA_02571 | Transporter (Major Facilitator Superfamily) | −2.16 | −2.24 |
CC_2804 | CCNA_02895 | TonB-dependent receptor | −2.41 | −2.22 |
CC_3161 | CCNA_03263 | TonB-dependent receptor | −2.89 | −2.68 |
CC_3335 | reannotated | Hypothetical protein | −4.54 | −5.88 |
CC_3336 | CCNA_03444 | TonB-dependent receptor | −2.51 | −2.38 |
Energy Metabolism | ||||
CC_0277 | CCNA_00279 | NAD(P)H dehydrogenase (quinone) | −3.11 | −4.74 |
CC_1401 | CCNA_01467 | Cytochrome cbb3 oxidase subunit I ccoN | −2.76 | −6.07 |
CC_1951 | CCNA_02028 | NTF2 enzyme family protein | −2.11 | −2.23 |
CC_1952 | CCNA_02029 | NADH-quinone oxidoreductase chain D | −2.18 | −2.23 |
CC_1954 | CCNA_02031 | NADH-quinone oxidoreductase chain C | −2.09 | −2.16 |
CC_2115 | CCNA_02200 | Cytochrome c-family protein | −3.02 | −4.61 |
CC_2494 | CCNA_02579 | Cytochrome P450 (Heme) | −3.31 | −4.43 |
CC_3526 | CCNA_03641 | Succinate dehydrogenase iron-sulfur protein (Fe-S cluster) | −2.35 | −3.12 |
CC_3527 | CCNA_03642 | Succinate dehydrogenase flavoprotein subunit | −2.84 | −2.95 |
CC_3528 | CCNA_03643 | Succinate dehydrogenase membrane anchor subunit | −3.11 | −3.29 |
CC_3529 | CCNA_03644 | Succinate dehydrogenase cytochrome B-556 subunit | −2.87 | −2.89 |
Miscellaneous | ||||
CC_1363 | CCNA_01425 | H+ translocating pyrophosphatase | −3.35 | −2.78 |
CC_2479 | CCNA_02564 | acyl-CoA dehydrogenase, short-chain specific | −2.38 | −2.29 |
CC_2518 | CCNA_02603 | Phosphatidylserine decarboxylase (DUF1254) | −3.05 | −4.79 |
CC_3085 | CCNA_03181 | Alcohol dehydrogenase (Zinc or iron) | −4.05 | −2.28 |
Regulators | ||||
CC_0752 | CCNA_00789 | Hypoxia transcriptional regulator FixK | −3.02 | −4.08 |
CC_0753 | CCNA_00790 | Hypoxia negative feedback regulator FixT | −2.63 | −3.65 |
CC_1410 | CCNA_01476 | CRP-family transcription regulator FtrB | −6.56 | −13.47 |