Skip to main content
Figure 2 | BMC Genomics

Figure 2

From: Transcription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines

Figure 2

Clustering of protein occupancy data. A: Hierarchically clustered heatmap of all DNA-associated proteins assayed. Each row represents a HOT region called on the pooled data by UniPeak (m = 11,239), and each column represents a single replicate of a ChIP-seq experiment (n = 503). The sidebars show histone modification ChIP-seq signals within the same regions, normalized separately, and initiating RNA polymerase II signal and the nearest peak within 500 bp (zero if there were no peaks in this range). Color intensity in the heatmaps corresponds to variance-stabilized values for occupancy. B: Canonical TFs only (7,227 regions × 357 samples).

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us