AUCs of different integrative methods for predicting in vivo TF binding. The first four bars are from our k-mer PBM data analysis method (black), simple baseline using only DNase data (red), or from PIPES (green and purple). Cyan bars: Simple overlapping approach that overlays PWM matches with DNase data. Orange bars: CENTIPEDE using S&W PWMs to scan sequences and an odd log score of log2(1000) as cutoff. See main text and also Additional file1 for more details.