TPM distribution for reproducible and irreproducible clusters. (A) The number of genes on the RefSeq hg18 genome annotated by reproducible and irreproducible clusters for HeLa cells by Kanamori-Katayama et al.  are represented at each TPM bin. Clusters with IDR < 0.1 were identified as reproducible clusters (green bars) and the other ones were classified into irreproducible clusters (orange). Within each group, the clusters were subdivided according to their TPM and plotted at each TPM bin. (B) The number of clusters not annotated to genes on the RefSeq hg18 genome for HeLa cells are represented in each TPM bin. These clusters do not overlap the RefSeq hg18 transcription start sites with ± 500 bp window size. Clusters were separated by the above method, and reproducible clusters are represented in green and irreproducible ones are orange.