Table 3 Enrichment of gene groups down-regulated in muscle-less humeri based on GO terms under subontologies biological process and cellular component
Gene ontology term | Gene count in study | Enrichment1 | |
|---|---|---|---|
Development/Differentiation | 155 | 2.73 × 10-15 to 0.0084 | |
GO:0048856: Anatomical structure development | 134 | 2.73 × 10-15 | |
GO:0032502: Developmental process | 155 | 1.52 × 10-14 | |
GO:0048513: Organ development | 107 | 4.23 × 10-13 | |
GO:0007275: Multicellular organismal development | 142 | 4.92 × 10-13 | |
GO:0048731: System development | 122 | 5.57 × 10-13 | |
GO:0009888: Tissue development | 58 | 8.37 × 10-13 | |
GO:0030154: Cell differentiation | 94 | 8.86 × 10-10 | |
GO:0048869: Cellular developmental process | 96 | 1.67 × 10-9 | |
GO:0048468: Cell development | 45 | 2.66 × 10-7 | |
GO:0009887: Organ morphogenesis | 38 | 6.12 × 10-5 | |
GO:0001756: Somitogenesis | 8 | 2.61 × 10-4 | |
GO:0035282: Segmentation | 9 | 2.66 × 10-4 | |
GO:0009952: Anterior/posterior pattern formation | 13 | 0.0033 | |
GO:0009790: Embryonic development | 34 | 0.0074 | |
GO:0043009: Chordate embryonic development | 24 | 0.0075 | |
GO:0009792: Embryonic development ending in birth | 24 | 0.0084 | |
Cytoskeleton | 30 | 5.30 × 10-19 to 0.0995 | |
Biological process | GO:0030029: Actin filament-based process | 25 | 1.45 × 10-9 |
GO:0030036: Actin cytoskeleton organization | 23 | 1.08 × 10-8 | |
GO:0007010: Cytoskeleton organization | 31 | 1.50 × 10-7 | |
GO:0007015: Actin filament organization | 5 | 0.0995 | |
GO:0015629: Actin cytoskeleton | 39 | 5.30 × 10-19 | |
Cellular component | GO:0005856: Cytoskeleton | 86 | 2.20 × 10-14 |
GO:0016459: Myosin complex | 21 | 1.26 × 10-15 | |
GO:0032982: Myosin filament | 11 | 2.32 × 10-12 | |
GO:0044430: Cytoskeletal part | 51 | 1.16 × 10-6 | |
GO:0005884: Actin filament | 5 | 0.0134 | |
Cell signalling | 31 | 4.78 × 10-5 to 0.0899 | |
GO:0007154: Cell communication | 32 | 4.78 × 10-5 | |
GO:0007267: Cell-cell signalling | 23 | 1.33 × 10-4 | |
GO:0007169: Transmembrane protein tyrosine kinase signalling | 17 | 3.85 × 10-4 | |
GO:0007167: Enzyme linked receptor protein signalling pathway | 20 | 0.0011 | |
GO:0008543: Fibroblast growth factor receptor signalling pathway | 5 | 0.0139 | |
GO:0045168: Cell-cell signalling involved in cell fate specification | 4 | 0.0271 | |
GO:0040036: Regulation of fibroblast growth factor signalling | 3 | 0.0451 | |
GO:0043409: Negative regulation of MAPKKK cascade | 3 | 0.0614 | |
GO:0007219: Notch signalling pathway | 5 | 0.0899 | |