Table 1 Numbers of significantly regulated genes, categorised according to which factors and/or interactions were significant in the three-way ANOVA
Category | Significant genes | Biological interpretation |
|---|---|---|
A Maternal nutrition | 368 (151) | Maternal nutritional status has an effect independent of leptin treatment and postweaning diet |
B Leptin treatment | 200 (90) | Leptin treatment has an effect independent of maternal nutritional status and postweaning diet |
C Postweaning diet | 990 (531) | Postweaning diet has an effect independent of maternal nutritional status and leptin treatment |
AB (2-way interaction) | 949 (503) | The effect of leptin treatment is dependent on maternal nutritional status (or vice versa) |
AC (2-way interaction) | 96 (18) | The effect of postweaning diet is dependent on maternal nutritional status (or vice versa) |
BC (2-way interaction) | 127 (74) | The effect of postweaning diet is dependent on leptin treatment (or vice versa) |
ABC (3-way interaction) | 7 (3) | The effects of all three factors are mutually dependent |
Uncategorised | 128 (59) | Although significant changes were detected by one-way ANOVA, no individual factor or interaction term was subsequently significant in a three-factor ANOVA |