Table 3 Summary of functions putatively encoded by genes in satratoxin clusters SC1, SC2, and SC3

SAT1-7711 SAT1-40293

1

Membrane protein, FAD binding protein, contains domain found in fungal squalene epoxidases and monoxygenases

Putative FAD binding domain-containing protein from Eutypa lata.

5e-58/49

cl19134 cl17314

SAT2-7711 SAT2-40293

2

NADPH-dependent short-chain dehydrogenase/reductase

Hypothetical protein from Setosphaeria turcica.

5e-124/53

cd05327

SAT3-7711 SAT3-40293

2

Classical short-chain reductase

Putative short chain dehydrogenase reductase protein from Eutypa lata

5e-124/67

cd05233

SAT4-7711 SAT4-40293

3

Putative integral membrane protein

Putative integral membrane protein from Eutypa lata.

7e-89/54

No conserved domains detected

SAT5-7711 SAT5-40293

1

Putative acetyltransferase

Putative trichothecene 3-o- protein Eutypa lata.

93-165/54

cl19241

SAT6-7711 SAT6-40293

1

A secretory lipase domain

Related to lipase 1 from Fusarium fujikuroi

1e-166/53

cl14925

SAT7-7711 SAT7-40293

1

Squalene epoxidase

Putative salicylate hydroxylase from Aspergillus ruber

5e-132/46

cl17314

SAT8-7711 SAT8-40293

3

Putative polyketide synthase with a conventional non-reducing architecture

Putative polyketide synthase from Aspergillus ruber

0.0/48

cd00833

SAT9-7711 SAT9-40293

2

Putative Cys6 transcriptional factor

Hypothetical protein from Sordaria macrospora

2e-25/33

No conserved domains detected

SAT10-7711 SAT10-40293

6

Putative protein containing four ankyrin repeats

Multiple ankyrin repeats single kh domain protein from Metarhizium anisopliae

5e-78/25

cd00204

7

SAT11-7711 SAT11-40293

5

Putative cytochrome P450 monooxygenase and a Tri4 paralog

Cytochrome P450 from Myrothecium roridum

0.0/78

cl12078

SAT12-7711 SAT12-40293

5

Putative 15-O-acetyltransferase Tri3

Hypothetical protein from Endocarpon pusillum

1e-91/36

cl06457

SAT13-7711 SAT13-40293

2

Putative reducing polyketide synthase

Putative polyketide synthase protein from Eutypa lata

0.0/57

cd00833

SAT14-7711 SAT14-40293

1

Sat14 and Sat16 are complete and truncated paralogs of the acetyltransferase Tri3

Predicted protein from Nectria haematococca

0.0/67

pfam13523

SAT15-7711 SAT15-40293

2

The zinc finger protein Sat15

LolU from Epichloe festucae

8e-25/38

No conserved domains detected

SAT16-7711 SAT16-40293

4

Sat14 and Sat16 are complete and truncated paralogs of the acetyltransferase Tri3

Trichothecene 15-O-acetyltransferase from Fusarium graminearum

9e-36/45

cl06457

3

SAT17-7711 SAT17-40293

5

TauD hydroxylase

Hypothetical protein from Tuber melanosporum

5e-67/39

pfam02668

SAT18-7711 SAT18-40293

4

Methyltransferase

Hypothetical protein from Cladophialophora psammophila

4e-35/28

cl16913

SAT19-7711 SAT19-40293

2

N-acetyltransferase

Hypothetical protein from Nectria haematococca

4e-25/30

cd04301

SAT20-7711 SAT20-40293

3

Cys6-type zinc finger

Hypothetical protein from Macrophomina phaseolina

3e-43/30

No conserved domains detected

4

SAT21-7711 SAT21-40293

6

MFS (Major Facilitator Superfamily)-type transporter

Hypothetical protein Gaeumannomyces graminis

2e-94/37

pfam07690