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Table 1 Fixation index (FI) and related statistics for different human gene sets

From: Uncovering adaptive evolution in the human lineage

  SNPs DAF ≥ 1% SNPs DAF ≥ 15% SNPs DAF ≥ 30% SNPs DAF ≥ 60%
Data set N FI DoS α N FI DoS α N FI DoS α N FI DoS α
All genes 8019 0.73 -0.074 -0.361 5859 0.88 -0.031 -0.142 4744 0.94 -0.013 -0.059 2766 1.00 0.001 0.002
Human accelerated 182 1.60 0.116 0.375 15 1.55 0.109 0.356 136 1.69 0.131 0.409 75 1.68 0.129 0.405
Human BS test 216 1.16 0.037 0.137 172 1.27 0.058 0.209 135 1.39 0.080 0.278 78 1.66 0.123 0.398
Rapidly evolving 166 1.25 0.056 0.202 123 1.27 0.06 0.213 101 1.2 0.045 0.167 64 1.20 0.044 0.163
Mammalian-specific 77 0.71 -0.079 -0.413 57 0.95 -0.014 -0.058 47 1.04 0.010 0.042 28 0.91 -0.023 -0.100
  1. Data are for genes with at least one polymorphic site. DoS: direction of selection; α: proportion of adaptive substitutions. SNP: single nucleotide polymorphism. DAF: derived allele frequency.