Table 1 List of the differentially expressed genes showing the highest fold changes (FCs) in pair-wise comparison of consecutive time points during Aspergillus nidulans growth on suberin
First time point of suberin incubation (between the control and second day of incubation on suberin) | Mid time point of suberin incubation (between the second and fourth days of incubation on suberin) | Last time point of suberin incubation (between the fourth and sixth days of incubation on suberin) | ||||||
|---|---|---|---|---|---|---|---|---|
FC | Gene # | Description | FC | Gene # | Description | FC | Gene # | Description |
Up-regulated | ||||||||
358.7 | AN6000 | Asperthecin polyketide synthase (aptA) | 31.8 | AN7369 | GMC oxidoreductase | 23.5 | AN9230 | Monooxygenase associated with secondary metabolism |
305.8 | AN5309 | Putative cutinase 1 (cut1) | 22.0 | AN10030 | Putative alkaline serine protease | 9.6 | AN6778 | MFS transporter |
278.8 | AN7962 | Metalloproteinase (pepJ) | 22.7 | AN9224 | Monooxygenase | 8.6 | AN10026 | Oxidoreductase |
252.5 | AN9042 | Mutanase | 21.7 | AN9493 | Putative acetyltransferase (ngn12) | 7.0 | AN11202 | Putative DMATS-type aromatic prenyltransferase |
107.4 | AN0012 | Glucuronan lyase A | 20.1 | AN9227 | Dioxygenase associated with secondary metabolism | 6.6 | AN8392 | Melibiase subfamily |
91.6 | AN7812 | Putative sterigmatocystin biosynthesis protein (stcN) | 19.4 | AN5348 | Fatty acyl-CoA reductase | 6.6 | AN8106 | Dioxygenase associated with secondary metabolism |
90.1 | AN7349 | Mutanase (mutA) | 18.7 | AN7613 | Putative chitinase | 6.4 | AN8473 | RNA polimerase II transcription factor |
58.5 | AN2623 | Acyl-CoA:6-aminopenicillanic-acid-acyltransferase (aatA) | 5.8 | AN8978 | Regulatory protein (alcR) | |||
46.7 | AN11013 | Probable sterigmatocystin biosynthesis P450 monooxygenase (stcL) | 16.4 | AN2690 | Putative β-1,3-glucanase | 5.5 | AN8084 | MFS transporter |
35.0 | AN3931 | Meiotic expression up-regulated protein 14 (pilB) | 5.0 | AN8520 | protein required for terrequinone A biosynthesis (tdiE) | |||
33.4 | AN6835 | NADPH-cytochrome P450 reductase | 16.2 | AN9232 | MFS transporter | 5.0 | AN3369 | Zn2-Cys6 transcription factor (clrB) |
32.8 | AN7811 | Putative sterigmatocystin biosynthesis protein (stcO) | 16.6 | AN9234 | Oxidoreductase associated with secondary metabolism | 4.9 | AN6747 | C2H2 type zinc finger transcription factor |
33 < FC < 87 | Predicted proteins and poorly characterised genes | 17 < FC < 147 | Predicted proteins and poorly characterised genes | 4 < FC < 8 | Predicted proteins and poorly characterised genes | |||
AN1532, AN8995, AN6476, AN9301, AN7235, AN2330, AN4825, AN2913, AN0461, AN8656, AN1666, AN0488, AN1952 | AN6020, AN4970, AN7958, AN7957, AN5292, AN5319, AN8037, AN1155, AN2400, AN2710, AN7655, AN8162, AN9235, AN11163, AN1946 | AN7419, AN7092, AN2779, AN3881, AN7091, AN7395, AN8955, AN2658, AN2859, AN1719, AN2376, AN5422 | ||||||
Down-regulated | ||||||||
-39.5 | AN0399 | Nitrate transporter (nrtB) | -18.6 | AN7824 | Probable sterigmatocystin biosynthesis P450 monooxygenase (stcB) | -13.1 | AN2583 | Glyceraldehyde 3-phosphate dehydrogenase |
-35.9 | AN1008 | Nitrate transporter (crnA) | -18.1 | AN8356 | Alcohol dehydrogenase | -9.8 | AN1666 | Nucleolar GTP-binding protein 2 |
-35.4 | AN1006 | Nitrate reductase (niaD) | -14.1 | AN7804 | Putative sterigmatocystin biosynthesis monooxygenase (stcW) | -8.6 | AN2861 | Putative F-box protein |
-26.1 | AN7539 | Hydrophobin | -12.6 | AN7818 | Probable sterigmatocystin biosynthesis P450 monooxygenase (stcF) | -6.3 | AN5228 | NADH:flavin oxidoreductase/NADH oxidase |
-24.4 | AN7392 | Choline transporter Hnm1 | -11.8 | AN7807 | Putative sterigmatocystin biosynthesis protein (stcT) | |||
-11.5 | AN7815 | Fatty acid synthase subunit α | -5.6 | AN4180 | MFS transporter | |||
-11.4 | AN5860 | MFS monosaccharide transporter (mstE) | ||||||
-24.1 | AN2859 | Dihydrodipicolinate synthetase | -11.2 | AN7825 | Putative sterigmatocystin biosynthesis polyketide synthase (stcA) | -5.6 | AN10619 | Glutamate decarboxylase |
-11.2 | AN4135 | Stearoyl-CoA desaturase (sdeB) | ||||||
-23.9 | AN4131 | Na+/H+ antiporter | -11.1 | AN7814 | Fatty acid synthase subunit β | -5.5 | AN7169 | Flavohemoprotein (fhbA) |
-23.8 | AN7278 | Glutamate decarboxylase | -10.8 | AN7806 | Versicolorin reductase | |||
-21.7 | AN4119 | MFS multidrug transporter | -10.6 | AN3763 | Siderochrome-iron transporter | -5.5 | AN3264 | MFS multidrug transporter |
-19.0 | AN3776 | MFS transporter | -10.0 | AN7811 | Putative sterigmatocystin biosynthesis protein (stcO) | |||
-61 < FC < -18 | Predicted proteins and poorly characterised genes | -28 < FC < -10 | Predicted protein and poorly characterised genes | -16 < FC < -5 | Predicted protein and poorly characterised genes | |||
AN2595, AN7214, AN5305, AN8081, AN6946, AN4108, AN7378, AN9220, AN6128, AN8981, AN3333, AN6930, AN4128, AN6932, AN8670 | AN7397, AN3251, AN8544, AN6661, AN7817, AN8314, AN2722, AN0169, AN7812, AN7809, AN7915, AN11013 | AN2571, AN9310, AN7949, AN5489, AN0421, AN0461, AN9102, AN9378, AN7960, AN3305, AN0728, AN0247, AN0288, AN8974, AN0838, AN8544, AN3314 | ||||||