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Table 2 Significantly differentially represented KEGG pathways (multiple testing corrected p ≤ 0.1) between wild and domesticated stocks in the two life stages, wild fish is considered as control

From: A comparison of gene transcription profiles of domesticated and wild Atlantic salmon (Salmo salar L.) at early life stages, reared under controlled conditions

  KEGG functional group KEGG sub-group KEGG pathway Direction of perturbation p-value Set size
Sac fry Cellular Processes Cell growth and death Oocyte meiosis Up regulated 0.00212 15
Environmental Information Processing Signal transduction Hippo signaling pathway Up regulated 0.00128 15
Environmental Information Processing Signal transduction Wnt signaling pathway Up regulated 0.00053 20
Genetic Information Processing Folding, sorting and degradation Protein processing in endoplasmic reticulum Up regulated 0.00186 36
Genetic Information Processing Translation Aminoacyl-tRNA biosynthesis Up regulated 0.00734 13
Genetic Information Processing Translation Ribosome Up regulated 0.00016 50
Genetic Information Processing Translation Ribosome biogenesis in eukaryotes Up regulated 0.00024 31
Genetic Information Processing Translation RNA transport Up regulated 0.00002 39
Cellular Processes Transport and catabolism Phagosome Down regulated 0.00042 37
Environmental Information Processing Signal transduction NF-kappa B signaling pathway Down regulated 0.00093 25
Environmental Information Processing Signaling molecules and interaction Cytokine-cytokine receptor interaction Down regulated ≤0.00001 26
Organismal Systems Immune system B cell receptor signaling pathway Down regulated 0.00133 16
Organismal Systems Immune system Chemokine signaling pathway Down regulated ≤0.00001 38
Organismal Systems Immune system Complement and coagulation cascades Down regulated 0.00385 21
Organismal Systems Immune system Fc epsilon RI signaling pathway Down regulated 0.00778 16
Organismal Systems Immune system Hematopoietic cell lineage Down regulated 0.00007 14
Organismal Systems Nervous system Glutamatergic synapse Down regulated 0.00152 19
Organismal Systems Nervous system Serotonergic synapse Down regulated 0.00303 16
Organismal Systems Nervous system Synaptic vesicle cycle Down regulated 0.00171 18
Metabolism Lipid metabolism Glycerophospholipid metabolism Down regulated 0.00781 10
Environmental Information Processing Signal transduction NF-kappa B signaling pathway Two way perturbed 0.00116 25
Environmental Information Processing Signal transduction TNF signaling pathway Two way perturbed 0.00368 19
Environmental Information Processing Signaling molecules and interaction Cytokine-cytokine receptor interaction Two way perturbed 0.00001 26
Environmental Information Processing Signaling molecules and interaction Neuroactive ligand-receptor interaction Two way perturbed 0.00371 23
Organismal Systems Development Osteoclast differentiation Two way perturbed 0.00555 28
Organismal Systems Immune system Chemokine signaling pathway Two way perturbed 0.00343 38
Organismal Systems Immune system NOD-like receptor signaling pathway Two way perturbed 0.00416 14
Organismal Systems Immune system Toll-like receptor signaling pathway Two way perturbed 0.00240 19
Metabolism Lipid metabolism Glycerophospholipid metabolism Two way perturbed 0.00275 10
Feeding fry Cellular Processes Transport and catabolism Peroxisome Up regulated 0.00014 27
Environmental Information Processing Signaling molecules and interaction ECM-receptor interaction Up regulated 0.01210 12
Organismal Systems Circulatory system Cardiac muscle contraction Up regulated 0.00939 20
Organismal Systems Digestive system Fat digestion and absorption Up regulated 0.00047 16
Organismal Systems Digestive system Pancreatic secretion Up regulated 0.00062 17
Organismal Systems Digestive system Protein digestion and absorption Up regulated 0.00004 23
Organismal Systems Endocrine system Adipocytokine signaling pathway Up regulated 0.00435 15
Organismal Systems Endocrine system Insulin signaling pathway Up regulated ≤0.00001 19
Organismal Systems Endocrine system PPAR signaling pathway Up regulated ≤0.00001 29
Metabolism Amino acid metabolism Arginine and proline metabolism Up regulated 0.00014 17
Metabolism Amino acid metabolism Glycine, serine and threonine metabolism Up regulated 0.00029 17
Metabolism Carbohydrate metabolism Glycolysis/Gluconeogenesis Up regulated 0.00001 25
Metabolism Carbohydrate metabolism Propanoate metabolism Up regulated 0.00084 12
Metabolism Energy metabolism Carbon fixation in photosynthetic organisms Up regulated 0.00091 12
Metabolism Energy metabolism Methane metabolism Up regulated 0.00048 12
Metabolism Energy metabolism Oxidative phosphorylation Up regulated 0.00058 59
Metabolism Lipid metabolism Biosynthesis of unsaturated fatty acids Up regulated 0.00004 12
Metabolism Lipid metabolism Fatty acid degradation Up regulated 0.00056 16
Metabolism Lipid metabolism Fatty acid elongation Up regulated 0.00742 11
Metabolism Lipid metabolism Glycerolipid metabolism Up regulated 0.00429 15
Environmental Information Processing Signal transduction Jak-STAT signaling pathway Down Regulated 0.00005 16
Environmental Information Processing Signal transduction NF-kappa B signaling pathway Down Regulated ≤0.00001 28
Environmental Information Processing Signaling molecules and interaction Cytokine-cytokine receptor interaction Down Regulated ≤0.00001 38
Environmental Information Processing Signaling molecules and interaction Neuroactive ligand-receptor interaction Down Regulated 0.00122 22
Organismal Systems Immune system Antigen processing and presentation Down Regulated 0.00267 22
Organismal Systems Immune system Chemokine signaling pathway Down Regulated ≤0.00001 35
Organismal Systems Immune system Cytosolic DNA-sensing pathway Down Regulated 0.00799 10
Organismal Systems Immune system Fc epsilon RI signaling pathway Down Regulated 0.00130 12
Organismal Systems Immune system Fc gamma R-mediated phagocytosis Down Regulated 0.00407 17
Organismal Systems Immune system Toll-like receptor signaling pathway Down Regulated 0.00055 17
Genetic Information Processing Folding, sorting and degradation Proteasome Down Regulated ≤0.00001 25
Environmental Information Processing Signaling molecules and interaction Cytokine-cytokine receptor interaction Two way perturbed ≤0.00001 38
  1. Set size is the number of genes included in the gene set test. Non-redundant pathways are shown in bold.