Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria

Table 4 Detected putative sactipeptide gene cluster

	Phylum	Locus tag of radical SAM	Similar to^†	Reference^#
Clostridium acetobutylicum DSM 1731	Firmicutes	SMB_G0673
Clostridium acetobutylicum ATCC 824	Firmicutes	CA_C0658
Clostridium acetobutylicum EA 2018	Firmicutes	CEA_G0670
Clostridium cellulolyticum H10	Firmicutes	Ccel_0328	thuricin	[37]
Clostridium difficile 630	Firmicutes	CD630_1620	thuricin	[37]
Clostridium kluyveri DSM 555	Firmicutes	CKL_0375
Clostridium lentocellum RHM5, DSM 5427	Firmicutes	Clole_0089
Clostridium thermocellum ATCC 27405	Firmicutes	Cthe_1695
Anaerococcus prevotii PC1, DSM 20548	Firmicutes	Apre_1837	thuricin	[37]
Ruminococcus albus 7, ATCC 27210	Firmicutes	Rumal_0164
Syntrophobotulus glycolicus FIGlyR, DSM 8271	Firmicutes	Sgly_1407
Thermoanaerobacter mathranii mathranii A3, DSM1142	Firmicutes	Tmath_1976	thuricin	[37]
Caldicellulosiruptor kristjanssonii 177R1B, DSM 12137	Firmicutes	Calkr_0222	thuricin	[37]
Halothermothrix orenii H 168	Firmicutes	Hore_04320
Desulfobacca acetoxidans ASRB2, DSM 111069	δ- Proteobacteria	Desac_0107
Thermosipho melanesiensis BI429	Thermotogae	Tmel_0409

^†Cluster shows similarities to characterized RiPP cluster; ^#Cluster was previously detected by genome mining approaches.

ISSN: 1471-2164