Skip to main content

Table 5 Detected LAP gene cluster

From: Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria

  Phylum Locus Tag of dehydrogenase Similar to Reference#
Clostridium botulinum A2 BoNT/A2 Kyoto-F Firmicutes CLM_0573 clostridiolysin S  
Clostridium botulinum A BoNT/A1 ATCC 19397 Firmicutes CLB_0528 clostridiolysin S  
Clostridium botulinum A BoNT/A1 Hall Firmicutes CLC_0561 clostridiolysin S  
Clostridium botulinum BoNT/B1 Okra Firmicutes CLD_0261 clostridiolysin S  
Clostridium botulinum BoNT/A3 Loch Maree Firmicutes CLK_3698 clostridiolysin S  
Clostridium botulinum Ba4 str. 657 Firmicutes CLJ_B0564 clostridiolysin S  
Clostridium botulinum F230613 Firmicutes CBF_0535 clostridiolysin S  
Clostridium botulinum H04402 065 Firmicutes H04402_00508 clostridiolysin S  
Clostridium botulinum A ATCC 3502 Firmicutes CBO0487 clostridiolysin S [50]
Clostridiumbotulinum F str. Langeland Firmicutes CLI_0567 clostridiolysin S  
Thermoanaerobacter mathranii mathranii A3, DSM 11426 Firmicutes Tmath_0475 **  
Brachyspira hyodysenteriae WA1 Spirochaetes BHWA1_02354   
Brachyspira pilosicoli 95/1000 Spirochaetes BP951000_0919 *  
Brachyspira intermedia PWS/A Spirochaetes Bint_2324 *  
Brachyspira murdochii 56150, DSM 12563 Spirochaetes Bmur_0997 *  
  1. *All strains share an identical precursor peptide sequence; **no precursor peptide could be annotated; Cluster shows similarities to characterized RiPP cluster; #Cluster was previously detected by genome mining approaches.