Figure 3

Conservation of CR1, CR2 and CR3 in all vertebrate classes. PCR amplification of different vertebrate genomic DNA samples using primers designed based on the human sequence. Lanes: M – size marker indicated in bp, hu – human, mo – mouse, ch – chicken, co – cobra, fr – frog and zf – zebra fish. The arrows indicate the corresponding products that have been confirmed by direct sequencing as well as Southern hybridization using human CRs as probe.