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Table 2 Summary of genes with enriched transcripts in unc-4:: GFP neurons. Genes are organized into categories according to molecular function (KOG or other description http://www.wormbase.org). Gene families or functional groups with potential functions in neurons are emphasized in this list. Statistical rank is indicated for each transcript.

From: A gene expression fingerprint of C. elegans embryonic motor neurons

Cosmid Name Common Name Rank KOG (Other description)
Axon Guidance and Outgrowth    
B0273.4a unc-5 934 Netrin transmembrane receptor unc-5
T19B4.7 unc-40 188 Receptor mediating netrin-dependent axon guidance
F41C6.1 unc-6 616 Netrin, axonal chemotropic factor
F56D1.4a clr-1 754 Protein tyrosine phosphatase
M79.1a abl-1 882 Protein tyrosine kinase
F09B9.2 unc-115 696 Actin-binding LIM Zn-finger protein Limatin involved in axon guidance
B0350.2 unc-44 449 Ankyrin
C01G10.11a unc-76 182 Kinesin-associated fasciculation and elongation protein involved in axonal transport
K10D3.2 unc-14 763 (RUN domain protein required for axonogenesis and sex myoblast migration)
Wingless Signaling    
K10B4.6 cwn-1 216 Wnt family of developmental regulators
Y71F9B.5a lin-17 899 Smoothened and related G-protein-coupled receptors (Frizzled Receptor)
Acetylcholine Receptor Subunits    
K11G12.2 acr-2 66 Acetylcholine receptor
R01E6.4 acr-12 292 Acetylcholine receptor
F21F3.5 unc-38 399 Acetylcholine receptor
T05C12.2 acr-14 782 Acetylcholine receptor
Y110A7A.3 unc-63 800 Acetylcholine receptor
F21A3.7   212 Acetylcholine receptor
Y105E8A.7 lev-10 323 Cubilin, multiligand receptor mediating cobalamin absorption
T14A8.1 ric-3 237 Unnamed protein (Required for nAChR assembly/trafficking)
Ligand-gated Ion Channel    
ZC196.7 glr-5 792 Glutamate-gated kainate-type ion channel receptor subunit GluR5 and related subunits
T27E9.9   41 Ligand-gated ion channel (glycine/GABA)
Y71D11A.5   502 Ligand-gated ion channel (glycine/GABA)
Y46G5A.30 snf-5 686 Sodium-neurotransmitter symporter
C09E8.1a   578 Sodium-neurotransmitter symporter
G-proteins    
M01D7.7a egl-30 124 G protein subunit Galphaq/Galphay, small G protein superfamily
F08B6.2 gpc-2 469 G protein gamma subunit
F56H9.4 gpa-9 638 G-protein alpha subunit (small G protein superfamily)
G-protein Pathway Components    
F28C1.2 egl-10 872 G protein signaling regulators
C05B5.7 rgs-1 486 G protein signaling regulators
F17C8.1 acy-1 884 Adenylyl cyclase
R07E4.6 kin-2 467 cAMP-dependent protein kinase types I and II, regulatory subunit
C17F4.6 gcy-19 213 Natriuretic peptide receptor, guanylate cyclase
C50H2.2 egl-47 432 (Gαo coupled receptor)
F57F5.5 pkc-1 747 Serine/threonine protein kinase
F39B2.8   928 Predicted membrane protein
C24A8.4   1010 STE20-like serine/threonine kinase MST
Neuropeptides    
W07E11.3 flp-2 31 Unnamed protein (FMRF-like peptide)
C18D1.3 flp-4 691 (FMRF-like peptide)
C03G5.7 flp-5 562 (FMRF-like peptide)
F33D4.3 flp-13 15 Unnamed protein (FMRF-like peptide)
E03D2.2 nlp-9 234 Unnamed protein (Neuropeptide-like protein)
CC4.2 nlp-15 165 Unnamed protein (Neuropeptide-like protein)
Y47D3B.2a nlp-21 254 Unnamed protein (Neuropeptide-like protein)
F13B12.5 ins-1 200 (Insulin-like peptide)
T28B8.2 ins-18 767 Unnamed protein (Insulin-like peptide)
F56A11.5   928 Uncharacterized Fe-S protein
Neuropeptide Processing and Secretion    
T03D8.3   613 Proprotein convertase (PC) 2 chaperone involved in secretion (neuroendocrine protein 7B2)
C32E8.7 ric-19 20 Secretory vesicle-associated protein ICA69, contains Arfaptin domain
ZK897.1 unc-31 588 Ca2+-dependent activator protein
Neuropeptide Receptor    
T05A1.1 npr-2 362 7 transmembrane receptor (neuropeptide receptor family)
F59D12.1   797 7 transmembrane receptor (rhodopsin-like GPCR)
T07D4.1   77 7 transmembrane receptor (rhodopsin-like GPCR)
Y62E10A.4   275 7-transmembrane receptor (rhodopsin-like GPCR)
K07E8.5   452 Unnamed protein (FMRF receptor)
C35A11.1   814 Unnamed protein (rhodopsin-like GPCR)
ZC84.4   708 7 transmembrane receptor (rhodopsin-like GPCR)
F56B6.5 uvt-6 629 7 transmembrane receptor (somatostatin receptor)
F56A11.5   928 Uncharacterized Fe-S protein (Neuropeptide receptor activity)