Downing C, Carosone-Link P, Bennett B, Johnson T: QTL mapping for low-dose ethanol activation in the LXS recombinant inbred strains. Alcohol Clin Exp Res. 2006, 30: 1111-1120. 10.1111/j.1530-0277.2006.00137.x.
Article
PubMed
CAS
Google Scholar
Bennett B, Carosone-Link P, Zahniser NR, Johnson TE: Confirmation and Fine Mapping of Ethanol Sensitivity QTLs, and Candidate Gene Testing in the LXS Recombinant Inbred Mice. J Pharmacol Exp Ther. 2006,
Google Scholar
Radcliffe RA, Floyd KL, Lee MJ: Rapid ethanol tolerance mediated by adaptations in acute tolerance in inbred mouse strains. Pharmacol Biochem Behav. 2006,
Google Scholar
Markel PD, Defries JC, Johnson TE: Use of repeated measures in an analysis of ethanol-induced loss of righting reflex in inbred long-sleep and short-sleep mice. Alcohol Clin Exp Res. 1995, 19: 299-304. 10.1111/j.1530-0277.1995.tb01506.x.
Article
PubMed
CAS
Google Scholar
Hanania T, McCreary AC, Haughey HM, Salaz DO, Zahniser NR: MK-801- and ethanol-induced activity in inbred long-sleep and short-sleep mice: dopamine and serotonin systems. Eur J Pharmacol. 2002, 457: 125-135. 10.1016/S0014-2999(02)02685-7.
Article
PubMed
CAS
Google Scholar
Hanania T, Zahniser NR: Locomotor activity induced by noncompetitive NMDA receptor antagonists versus dopamine transporter inhibitors: opposite strain differences in inbred long-sleep and short-sleep mice. Alcohol Clin Exp Res. 2002, 26: 431-440. 10.1111/j.1530-0277.2002.tb02558.x.
Article
PubMed
CAS
Google Scholar
Owens JC, Stallings MC, Johnson TE: Genetic analysis of low-dose ethanol-induced activation (LDA) in inbred long sleep (ILS) and inbred short sleep (ISS) mice. Behav Genet. 2002, 32: 163-171. 10.1023/A:1016018411202.
Article
PubMed
Google Scholar
Ehringer MA, Thompson J, Conroy O, Goldman D, Smith TL, Schuckit MA, Sikela JM: Human alcoholism studies of genes identified through mouse quantitative trait locus analysis. Addict Biol. 2002, 7: 365-371. 10.1080/1355621021000005496.
Article
PubMed
CAS
Google Scholar
Crabbe JC, Metten P, Yu CH, Schlumbohm JP, Cameron AJ, Wahlsten D: Genotypic differences in ethanol sensitivity in two tests of motor incoordination. J Appl Physiol. 2003, 95: 1338-1351.
Article
PubMed
CAS
Google Scholar
Xu Y, Ehringer M, Yang F, Sikela JM: Comparison of Global Brain Gene Expression Profiles Between Inbred Long-Sleep and Inbred Short-Sleep Mice by High-Density Gene Array Hybridization. Alcohol Clin Exp Res. 2001, 25: 810-818. 10.1111/j.1530-0277.2001.tb02284.x.
Article
PubMed
CAS
Google Scholar
Schmahmann JD: Disorders of the cerebellum: ataxia, dysmetria of thought, and the cerebellar cognitive affective syndrome. J Neuropsychiatry Clin Neurosci. 2004, 16: 367-378.
Article
PubMed
Google Scholar
Maier SE, Miller JA, West JR: Prenatal binge-like alcohol exposure in the rat results in region-specific deficits in brain growth. Neurotoxicol Teratol. 1999, 21: 285-291. 10.1016/S0892-0362(98)00056-7.
Article
PubMed
CAS
Google Scholar
Schneider F, Habel U, Wagner M, Franke P, Salloum JB, Shah NJ, Toni I, Sulzbach C, Honig K, Maier W, Gaebel W, Zilles K: Subcortical correlates of craving in recently abstinent alcoholic patients. Am J Psychiatry. 2001, 158: 1075-1083. 10.1176/appi.ajp.158.7.1075.
Article
PubMed
CAS
Google Scholar
Volkow ND, Wang GJ, Fowler JS, Hitzemann R, Angrist B, Gatley SJ, Logan J, Ding YS, Pappas N: Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction. Am J Psychiatry. 1999, 156: 19-26.
Article
PubMed
CAS
Google Scholar
Olbrich HM, Valerius G, Paris C, Hagenbuch F, Ebert D, Juengling FD: Brain activation during craving for alcohol measured by positron emission tomography. Aust N Z J Psychiatry. 2006, 40: 171-178. 10.1111/j.1440-1614.2006.01765.x.
Article
PubMed
Google Scholar
Pandey SC: Neuronal signaling systems and ethanol dependence. Mol Neurobiol. 1998, 17: 1-15.
Article
PubMed
CAS
Google Scholar
Pandey SC, Zhang H, Roy A, Xu T: Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism. J Clin Invest. 2005, 115: 2762-2773. 10.1172/JCI24381.
Article
PubMed
CAS
PubMed Central
Google Scholar
Melis M, Camarini R, Ungless MA, Bonci A: Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure. J Neurosci. 2002, 22: 2074-2082.
PubMed
CAS
Google Scholar
Mailliard WS, Diamond I: Recent advances in the neurobiology of alcoholism: the role of adenosine. Pharmacol Ther. 2004, 101: 39-46. 10.1016/j.pharmthera.2003.10.002.
Article
PubMed
CAS
Google Scholar
Asher O, Cunningham TD, Yao L, Gordon AS, Diamond I: Ethanol stimulates cAMP-responsive element (CRE)-mediated transcription via CRE-binding protein and cAMP-dependent protein kinase. J Pharmacol Exp Ther. 2002, 301: 66-70. 10.1124/jpet.301.1.66.
Article
PubMed
CAS
Google Scholar
Kuo WP, Kim EY, Trimarchi J, Jenssen TK, Vinterbo SA, Ohno-Machado L: A primer on gene expression and microarrays for machine learning researchers. J Biomed Inform. 2004, 37: 293-303. 10.1016/j.jbi.2004.07.002.
Article
PubMed
CAS
Google Scholar
MacLaren EJ, Sikela JM: Cerebellar gene expression profiling and eQTL analysis in inbred mouse strains selected for ethanol sensitivity. Alcohol Clin Exp Res. 2005, 29: 1568-1579. 10.1097/01.alc.0000179376.27331.ac.
Article
PubMed
CAS
Google Scholar
Ding CH, Dubchak I: Multi-class protein fold recognition using support vector machines and neural networks. Bioinformatics. 2001, 17: 349-358. 10.1093/bioinformatics/17.4.349.
Article
PubMed
CAS
Google Scholar
Chen XL, Kunsch C: Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases. Curr Pharm Des. 2004, 10: 879-891. 10.2174/1381612043452901.
Article
PubMed
CAS
Google Scholar
Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M: Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells. 2001, 6: 857-868. 10.1046/j.1365-2443.2001.00469.x.
Article
PubMed
CAS
Google Scholar
Quinlan R: C4.5: Programs for Machine Learning. 1993, Morgan Kaufmann Publishers, San Mateo, CA
Google Scholar
Cho-Chung YS, Park YG, Nesterova M, Lee YN, Cho YS: CRE-decoy oligonucleotide-inhibition of gene expression and tumor growth. Mol Cell Biochem. 2000, 212: 29-34. 10.1023/A:1007144618589.
Article
PubMed
CAS
Google Scholar
Karlin S, Ost F, Blaisdell BE: Patterns in DNA and amino acid sequences and their statistical significance. Mathematical Methods for DNA Sequences. 1989, Waterman MS, CRC Press, 133-157.
Google Scholar
Kohavi R: A study of cross-validation and bootstrap for accuracy estimation and model selection. Proc. 14th International Joint Conference on Arificial Intelligence, Montreal, Canada. 1995, San Francisco: Morgan Kaufmann, 1137-1143.
Google Scholar
Witten IH, Frank E: Data Mining: Practical Machine Learning Tools and Techniques with Java Implementations. 2000, Morgan Kaufmann, San Francisco, CA
Google Scholar
Eggers A, Caudevilla C, Asins G, Hegardt FG, Serra D: Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase promoter contains a CREB binding site that regulates cAMP action in Caco-2 cells. Biochem J. 2000, 345: 201-206. 10.1042/0264-6021:3450201.
Article
PubMed
CAS
PubMed Central
Google Scholar
Muller F, Tora L: The multicoloured world of promoter recognition complexes. EMBO J. 2004, 23: 2-8. 10.1038/sj.emboj.7600027.
Article
PubMed
PubMed Central
Google Scholar
Carlezon WA, Duman RS, Nestler EJ: The many faces of CREB. Trends Neurosci. 2005, 28: 436-445. 10.1016/j.tins.2005.06.005.
Article
PubMed
CAS
Google Scholar
Gonzalez GA, Montminy MR: Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell. 1989, 59: 675-680. 10.1016/0092-8674(89)90013-5.
Article
PubMed
CAS
Google Scholar
Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS: Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol Cell Biol. 1994, 14: 6107-6116.
Article
PubMed
CAS
PubMed Central
Google Scholar
Weiss F, Koob GF: Drug addiction: functional neurotoxicity of the brain reward systems. Neurotox Res. 2001, 3: 145-156.
Article
PubMed
CAS
Google Scholar
Cha-Molstad H, Keller DM, Yochum GS, Impey S, Goodman RH: Cell-type-specific binding of the transcription factor CREB to the cAMP-response element. Proc Natl Acad Sci USA. 2004, 101: 13572-13577. 10.1073/pnas.0405587101.
Article
PubMed
CAS
PubMed Central
Google Scholar
McClung CA, Nestler EJ: Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci. 2003, 6: 1208-1215. 10.1038/nn1143.
Article
PubMed
CAS
Google Scholar
Mayr B, Montminy M: Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol. 2001, 2: 599-609. 10.1038/35085068.
Article
PubMed
CAS
Google Scholar
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S: Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest. 2004, 114: 1248-1259. 10.1172/JCI200421146.
Article
PubMed
CAS
PubMed Central
Google Scholar
Witschi H, Espiritu I, Maronpot RR, Pinkerton KE, Jones AD: The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis. 1997, 18: 2035-2042. 10.1093/carcin/18.11.2035.
Article
PubMed
CAS
Google Scholar
Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S: Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 2002, 62: 5196-5203.
PubMed
CAS
Google Scholar
[http://www.genome.ucsc.edu]
Keene SE: Elements of CLOS programs. Object-Oriented Programming in Common Lisp. Symbolics Incorporated (and Addison-Wesley). 1989, 5-14.
Google Scholar
[http://www.cs.waikato.ac.nz/ml/weka/]
Bengio Y, Nadeau C: Inference for the generalization error. Machine Learning. 2003, 52: 239-281. 10.1023/A:1024068626366.
Article
Google Scholar
Tukey JW: Exploratory Data Analysis (Limited Preliminary Edition). 1970, Reading MA: Addison-Wesley, II:
Google Scholar
Chambers JM, Cleveland WS, Kleiner B, Tukey PA: Graphical Methods for Data Analysis. 1983, Wadsworth & Brooks/Cole
Google Scholar
[http://www.r-project.org/]