Figure 5

Pie charts of genes clustered according to their cellular functions. (A) All genes present on the microarray. (B) Genes detected to be downregulated in the femAB+ backcross BB1305. Overrepresented categories as determined by Fisher's exact test comprised transport/binding proteins and lipoproteins (a), protein synthesis (b), metabolism of lipids (c), and metabolism of nucleotides (d). (C) Upregulated genes in BB1305 with statistically overrepresented categories included metabolism of amino acids (e), metabolism of carbohydrates (f), pathogenic factors (g), and phage-related functions (h). 1) Cell envelope other comprises cell division, germination, sporulation, and transformation/competence; 2) DNA-related functions comprise DNA modification, repair, recombination, replication, packaging, and segregation; 3) Miscellaneous comprises also detoxification, transposon and IS.