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Table 1 Morphological characteristics of primary branches of the saphenous artery

From: Vascular microarray profiling in two models of hypertension identifies caveolin-1, Rgs2 and Rgs5 as antihypertensive targets

Parameter

WKY

ACTH

SHR

Systolic BP (mmHg)

123 ± 5 (5)

146 ± 3* (10)

187 ± 4* (9)

Circumference (μm)

745 ± 36 (4)

628 ± 51 (7)

610 ± 22 (6)

Mean SMC layers

7.2 ± 0.1 (4)

6.7 ± 0.4 (7)

8.7 ± 0.4* (5)

Area of EC (μm2)

392 ± 9 (5)

438 ± 13* (6)

279 ± 4* (3)

MEGJs/EC

0.1 ± 0.08 (4)

0.06 ± 0.04 (4)

0.03 ± 0.03 (3)

  1. Mean ± SEM; number of animals in parentheses. *p < 0.05 compared to WKY. Myoendothelial gap junctions (MEGJs) are expressed per endothelial cell (EC). Measurement of EC area from 150 cells (WKY), 76 cells (ACTH) and 45 cells (SHR). SMC = smooth muscle cell. Data for WKY from reference [49].
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BMC Genomics

ISSN: 1471-2164

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